2. Others Membrane Transporter/Ion Channel
  3. Isotope-Labeled Compounds Potassium Channel
  4. Repaglinide-d5

Repaglinide-d5  (Synonyms: AG-EE 623ZW d5)

Cat. No.: HY-15209S Purity: 99.87%
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Repaglinide-d5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1].

For research use only. We do not sell to patients.

Repaglinide-d<sub>5</sub> Chemical Structure

Repaglinide-d5 Chemical Structure

CAS No. : 1217709-85-7

Size Price Stock Quantity
1 mg USD 270 In-stock
5 mg USD 540 In-stock
10 mg USD 810 In-stock
25 mg USD 1458 In-stock
50 mg USD 2187 In-stock
100 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

Other Forms of Repaglinide-d5:

Repaglinide-d5 Related Antibodies

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Description

Repaglinide-d5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1].

In Vitro

Repaglinide reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Repaglinide-d5 Related Antibodies
Molecular Weight

457.62

Formula

C27H31D5N2O4
CAS No.
Unlabeled CAS

135062-02-1
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(CC(N[C@H](C2=CC=CC=C2N3CCCCC3)CC(C)C)=O)C=C1OC([2H])([2H])C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (109.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 50 mg/mL (109.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1852 mL 10.9261 mL 21.8522 mL
5 mM 0.4370 mL 2.1852 mL 4.3704 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.1852 mL 10.9261 mL 21.8522 mL 54.6305 mL
5 mM 0.4370 mL 2.1852 mL 4.3704 mL 10.9261 mL
10 mM 0.2185 mL 1.0926 mL 2.1852 mL 5.4630 mL
15 mM 0.1457 mL 0.7284 mL 1.4568 mL 3.6420 mL
20 mM 0.1093 mL 0.5463 mL 1.0926 mL 2.7315 mL
25 mM 0.0874 mL 0.4370 mL 0.8741 mL 2.1852 mL
30 mM 0.0728 mL 0.3642 mL 0.7284 mL 1.8210 mL
40 mM 0.0546 mL 0.2732 mL 0.5463 mL 1.3658 mL
50 mM 0.0437 mL 0.2185 mL 0.4370 mL 1.0926 mL
60 mM 0.0364 mL 0.1821 mL 0.3642 mL 0.9105 mL
80 mM 0.0273 mL 0.1366 mL 0.2732 mL 0.6829 mL
100 mM 0.0219 mL 0.1093 mL 0.2185 mL 0.5463 mL
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Repaglinide-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Repaglinide-d51217709-85-7AG-EE 623ZW d5Isotope-Labeled CompoundsPotassium ChannelKcsAinsulinsecretagoguetype-2diabetesmellitusInhibitorinhibitorinhibit

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