2. Others NF-κB Autophagy Epigenetics Cell Cycle/DNA Damage Apoptosis Anti-infection
  3. Isotope-Labeled Compounds IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2
  4. Resveratrol-d4

Resveratrol-d4  (Synonyms: trans-Resveratrol-d4; SRT501-d4)

Cat. No.: HY-16561S Purity: ≥99.0%
COA Handling Instructions

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Resveratrol-d4 is the deuterium labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

For research use only. We do not sell to patients.

Resveratrol-d<sub>4</sub> Chemical Structure

Resveratrol-d4 Chemical Structure

CAS No. : 1089051-56-8

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1 mg（4.31 mM * 1 mL in Ethanol） USD 874 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Resveratrol-d4:

Resveratrol-d4 Related Antibodies

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Description

Resveratrol-d4 is the deuterium labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Resveratrol-d4 Related Antibodies
Molecular Weight

232.27

Formula

C14H8D4O3
CAS No.
Unlabeled CAS

501-36-0
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC1=CC(/C=C/C2=C([2H])C([2H])=C(O)C([2H])=C2[2H])=CC(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

DMF : ≥ 100 mg/mL (430.53 mM)

DMF : ≥ 100 mg/mL (430.53 mM)

Ethanol : ≥ 50 mg/mL (215.27 mM)

DMSO : ≥ 50 mg/mL (215.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 50 mg/mL (215.27 mM)

DMSO : ≥ 50 mg/mL (215.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / Ethanol / DMSO / DMF / DMF 1 mM 4.3053 mL 21.5267 mL 43.0533 mL 107.6334 mL
5 mM 0.8611 mL 4.3053 mL 8.6107 mL 21.5267 mL
10 mM 0.4305 mL 2.1527 mL 4.3053 mL 10.7633 mL
15 mM 0.2870 mL 1.4351 mL 2.8702 mL 7.1756 mL
20 mM 0.2153 mL 1.0763 mL 2.1527 mL 5.3817 mL
25 mM 0.1722 mL 0.8611 mL 1.7221 mL 4.3053 mL
30 mM 0.1435 mL 0.7176 mL 1.4351 mL 3.5878 mL
40 mM 0.1076 mL 0.5382 mL 1.0763 mL 2.6908 mL
50 mM 0.0861 mL 0.4305 mL 0.8611 mL 2.1527 mL
60 mM 0.0718 mL 0.3588 mL 0.7176 mL 1.7939 mL
80 mM 0.0538 mL 0.2691 mL 0.5382 mL 1.3454 mL
100 mM 0.0431 mL 0.2153 mL 0.4305 mL 1.0763 mL
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Resveratrol-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resveratrol-d41089051-56-8trans-Resveratrol-d4SRT501-d4Isotope-Labeled CompoundsIKKAutophagyMitophagySirtuinApoptosisBacterialFungalAntibioticKeap1-Nrf2IκB kinaseI kappa B kinase Mitochondrial AutophagyInhibitorinhibitorinhibit

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