2. Others Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage Autophagy
  3. Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy
  4. Retinoic acid-d3

Retinoic acid-d3  (Synonyms: Vitamin A acid-d3; all-trans-Retinoic acid-d3; ATRA-d3)

Cat. No.: HY-14649S5
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Retinoic acid-d3 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

For research use only. We do not sell to patients.

Retinoic acid-d<sub>3</sub> Chemical Structure

Retinoic acid-d3 Chemical Structure

CAS No. : 154461-49-1

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Other Forms of Retinoic acid-d3:

Retinoic acid-d3 Related Antibodies

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Description

Retinoic acid-d3 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2][3].

Molecular Weight

303.45

Formula

C20H25D3O2
CAS No.
Unlabeled CAS
SMILES

CC(/C=C/C=C(/C=C/C1=C(CCCC(C)1C)C([2H])([2H])[2H])C)=C\C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Retinoic acid-d3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Retinoic acid-d3154461-49-1Vitamin A acid-d3 all-trans-Retinoic acid-d3 ATRA-d3Isotope-Labeled CompoundsRAR/RXRPPAREndogenous MetaboliteAutophagyRetinoic acid receptorsRetinoid X receptorsPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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