2. Anti-infection
  3. Bacterial Influenza Virus Antibiotic
  4. Rifampicin-d4

Rifampicin-d4  (Synonyms: Rifampin-d4; Rifamycin AMP-d4)

Cat. No.: HY-B0272S2 Purity: 99.69%
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Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

For research use only. We do not sell to patients.

Rifampicin-d<sub>4</sub> Chemical Structure

Rifampicin-d4 Chemical Structure

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1 mg USD 510 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Rifampicin-d4:

Rifampicin-d4 Related Antibodies

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Description

Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Rifampicin-d4 Related Antibodies
Molecular Weight

826.96

Formula

C43H54D4N4O12
Unlabeled CAS

13292-46-1
Appearance

Solid

Color

White to off-white

SMILES

OC(C(/C=N/N1C([2H])([2H])CN(C)CC1([2H])[2H])=C(NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@@H](C)[C@H]2O)O)C)=O)C(O)=C3C(O)=C4C)=C3C5=C4O[C@](C)(O/C=C/[C@@H]([C@H]([C@@]([C@@H]2C)([H])OC(C)=O)C)OC)C5=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 20 mg/mL (24.18 mM)

DMF : ≥ 20 mg/mL (24.18 mM)

DMSO : ≥ 3.3 mg/mL (3.99 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 3.3 mg/mL (3.99 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF:PBS(pH 7.2)(1:1) : ≥ 0.5 mg/mL (0.60 mM)

Ethanol : ≥ 0.12 mg/mL (0.15 mM)

Ethanol : ≥ 0.12 mg/mL (0.15 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2092 mL 6.0462 mL 12.0925 mL
5 mM 0.2418 mL 1.2092 mL 2.4185 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO / DMF / DMF 1 mM 1.2092 mL 6.0462 mL 12.0925 mL 30.2312 mL
DMF / DMF 5 mM 0.2418 mL 1.2092 mL 2.4185 mL 6.0462 mL
10 mM 0.1209 mL 0.6046 mL 1.2092 mL 3.0231 mL
15 mM 0.0806 mL 0.4031 mL 0.8062 mL 2.0154 mL
20 mM 0.0605 mL 0.3023 mL 0.6046 mL 1.5116 mL
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Rifampicin-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rifampicin-d4Rifampin-d4Rifamycin AMP-d4BacterialInfluenza VirusAntibioticInhibitorinhibitorinhibit

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