rno-miR-345-5p antagomir

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rno-miR-345-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

For research use only. We do not sell to patients.

RNA, (GCACUGGACUAGGGGUCAG) (2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

rno-miR-345-5p antagomir Chemical Structure

Size	Price	Stock	Quantity
5 nmol	USD 225	Get quote 1-2 weeks 1-2 weeks 1-2 weeks	Estimated Time of Arrival: December 31
20 nmol	USD 450	Get quote 1-2 weeks 1-2 weeks 1-2 weeks	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of rno-miR-345-5p antagomir:

rno-miR-345-5p inhibitor Get quote

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Description	rno-miR-345-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Molecular Weight	7141.64
miRBase Accession Number	MI0000631
Mature miRNA Sequence	UGCUGACCCCUAGUCCAGUGC
Stem-loop ID	rno-mir-345
Stem-loop Sequence	ACCCAAGUCCAGGCCUGCUGACCCCUAGUCCAGUGCUUGUGGUGGCUACUGGGCCCUGAACUAGGGGUCUGGAGACCUGGGUUUGAUCUCCACAGG
Species	Rat
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (229 KB) Handling Instructions (2659 KB)