2. Immunology/Inflammation
  3. Thrombopoietin Receptor
  4. Romiplostim

Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues.

For research use only. We do not sell to patients.

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Based on 1 publication(s) in Google Scholar

Romiplostim Related Antibodies

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  • Purity & Documentation

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Description

Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues[1].

IC50 & Target

TPO (thrombopoietin protein)
Appearance

Liquid

Color

Colorless to light yellow

Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Fusion - IGHG1 Fc (Fragment constant) - [peptide 14-mer - peptide 14-mer]2
Biological Activity
  • Loaded Romiplostim on AHC2 biosensor, can bind C-MPL Protein, Human (HEK293, His, HY-P78002) with an affinity constant of 3.144E-08 M as determined in BLI assay.
Purity & Documentation
References
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Romiplostim Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RomiplostimThrombopoietin ReceptorInhibitorinhibitorinhibit

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Romiplostim
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HY-P990685
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