2. Metabolic Enzyme/Protease Autophagy Membrane Transporter/Ion Channel Anti-infection
  3. HMG-CoA Reductase (HMGCR) Autophagy Potassium Channel Bacterial
  4. Rosuvastatin Calcium (Standard)

Rosuvastatin Calcium (Standard)  (Synonyms: Rosuvastatin hemicalcium (Standard); ZD 4522 Calcium (Standard))

Cat. No.: HY-17504R Purity: 99.94%
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Rosuvastatin (Calcium) (Standard) is the analytical standard of Rosuvastatin (Calcium). This product is intended for research and analytical applications. Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

For research use only. We do not sell to patients.

Rosuvastatin Calcium (Standard) Chemical Structure

Rosuvastatin Calcium (Standard) Chemical Structure

CAS No. : 147098-20-2

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Description

Rosuvastatin (Calcium) (Standard) is the analytical standard of Rosuvastatin (Calcium). This product is intended for research and analytical applications. Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

Molecular Weight

520.61

Formula

C₂₂H₂₇CaFN₃O₆S-
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Rosuvastatin Calcium (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rosuvastatin Calcium (Standard)147098-20-2Rosuvastatin hemicalcium (Standard) ZD 4522 Calcium (Standard)HMG-CoA Reductase (HMGCR)AutophagyPotassium ChannelBacterialKcsAInhibitorinhibitorinhibit

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