2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. RuBi-Glutamate hexafluorophosphate sodium

RuBi-Glutamate hexafluorophosphate sodium 

Cat. No.: HY-131885 Purity: 82.94%
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RuBi-Glutamate hexafluorophosphate sodium is a novel cage glutamate compound based on ruthenium photochemistry. RuBi-Glutamate hexafluorophosphate sodium can be excited at visible wavelengths and release glutamate after single or two-photon excitation. It has high quantum efficiency and can be used at low concentrations, partially avoiding the blocking of GABA energy transmission by other cage compounds. Two-photon release of RuBi-Glutamate hexafluorophosphate sodium has high spatial resolution and produces a physiodynamic excitatory response in a single dendritic spine.

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RuBi-Glutamate hexafluorophosphate sodium Chemical Structure

RuBi-Glutamate hexafluorophosphate sodium Chemical Structure

CAS No. : 2417096-44-5

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RuBi-Glutamate hexafluorophosphate sodium Related Antibodies

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Description

RuBi-Glutamate hexafluorophosphate sodium is a novel cage glutamate compound based on ruthenium photochemistry. RuBi-Glutamate hexafluorophosphate sodium can be excited at visible wavelengths and release glutamate after single or two-photon excitation. It has high quantum efficiency and can be used at low concentrations, partially avoiding the blocking of GABA energy transmission by other cage compounds. Two-photon release of RuBi-Glutamate hexafluorophosphate sodium has high spatial resolution and produces a physiodynamic excitatory response in a single dendritic spine[1].

Molecular Weight

970.54

Formula

C28H32F12N5Na2O4P3Ru
CAS No.
Appearance

Solid

Color

Orange to red

SMILES

[F-][P+5]([F-])([F-])([F-])([F-])[F-].O=C(O[Na])[C@H](CCC(O[Na])=O)[NH2][Ru+2]12([N]3=CC=CC=C3C4=CC=CC=[N]14)([N]5=CC=CC=C5C6=CC=CC=[N]26)[P](C)(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 19.41 mg/mL (20.00 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0304 mL 5.1518 mL 10.3035 mL
5 mM 0.2061 mL 1.0304 mL 2.0607 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0304 mL 5.1518 mL 10.3035 mL 25.7589 mL
5 mM 0.2061 mL 1.0304 mL 2.0607 mL 5.1518 mL
10 mM 0.1030 mL 0.5152 mL 1.0304 mL 2.5759 mL
15 mM 0.0687 mL 0.3435 mL 0.6869 mL 1.7173 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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RuBi-Glutamate hexafluorophosphate sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RuBi-Glutamate hexafluorophosphate2417096-44-5GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorRuBi-GABARutheniumBipyridineUncagingInhibitorinhibitorinhibit

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