2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. S 24795

S 24795 is a partial agonist of α7 nAChR and improves mnemonic function in aged mice for the research of aging-related memory disturbances.

For research use only. We do not sell to patients.

S 24795 Chemical Structure

S 24795 Chemical Structure

CAS No. : 304679-75-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 89 In-stock
Solution
10 mM * 1 mL in DMSO USD 89 In-stock
Solid
5 mg USD 81 In-stock
10 mg USD 130 In-stock
25 mg USD 300 In-stock
50 mg USD 480 In-stock
100 mg USD 755 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

S 24795 is a partial agonist of α7 nAChR and improves mnemonic function in aged mice for the research of aging-related memory disturbances[1].

Molecular Weight

418.07

Formula

C14H13BrINO
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(CC1=[N+](C)C=CC=C1)C2=CC=C(C=C2)Br.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (298.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3919 mL 11.9597 mL 23.9194 mL
5 mM 0.4784 mL 2.3919 mL 4.7839 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3919 mL 11.9597 mL 23.9194 mL 59.7986 mL
5 mM 0.4784 mL 2.3919 mL 4.7839 mL 11.9597 mL
10 mM 0.2392 mL 1.1960 mL 2.3919 mL 5.9799 mL
15 mM 0.1595 mL 0.7973 mL 1.5946 mL 3.9866 mL
20 mM 0.1196 mL 0.5980 mL 1.1960 mL 2.9899 mL
25 mM 0.0957 mL 0.4784 mL 0.9568 mL 2.3919 mL
30 mM 0.0797 mL 0.3987 mL 0.7973 mL 1.9933 mL
40 mM 0.0598 mL 0.2990 mL 0.5980 mL 1.4950 mL
50 mM 0.0478 mL 0.2392 mL 0.4784 mL 1.1960 mL
60 mM 0.0399 mL 0.1993 mL 0.3987 mL 0.9966 mL
80 mM 0.0299 mL 0.1495 mL 0.2990 mL 0.7475 mL
100 mM 0.0239 mL 0.1196 mL 0.2392 mL 0.5980 mL
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S 24795 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S 24795304679-75-2S24795S-24795nAChRNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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