2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2 nsp14-IN-4

SARS-CoV-2 nsp14-IN-4 (Compound 12q) is an inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50=19 nM). SARS-CoV-2 nsp14-IN-4 is non-cytotoxic and cell-permeable. SARS-CoV-2 nsp14-IN-4 is used in COVID-19 research.

For research use only. We do not sell to patients.

SARS-CoV-2 nsp14-IN-4 Chemical Structure

SARS-CoV-2 nsp14-IN-4 Chemical Structure

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SARS-CoV-2 nsp14-IN-4 Related Antibodies

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Description

SARS-CoV-2 nsp14-IN-4 (Compound 12q) is an inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50=19 nM). SARS-CoV-2 nsp14-IN-4 is non-cytotoxic and cell-permeable. SARS-CoV-2 nsp14-IN-4 is used in COVID-19 research[1].

IC50 & Target

IC50: 19 nM (SARS-CoV-2 nsp14 methyltransferase)[1]
In Vitro

SARS-CoV-2 nsp14-IN-4 (5 μM, 60 min) shows excellent stability in microsomes, both mouse and human[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SARS-CoV-2 nsp14-IN-4 Related Antibodies
Molecular Weight

625.65

Formula

C31H27N7O6S
SMILES

O[C@H]1[C@@H](O)[C@H](N2C=C(C#CC3=CC4=CC=CC=C4N=C3)C(C2=NC=N5)=C5N)O[C@@H]1CN(C)S(C6=CC=C(OC)C(C#N)=C6)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV-2 nsp14-IN-4 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 nsp14-IN-4SARS-CoVSARS coronavirusCOVID-19SARS-CoV-2Inhibitorinhibitorinhibit

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