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SCP1-IN-2 (Compound SH T-65) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-2 promotes REST degradation and reduces transcriptional activity. A high level of REST protein drives the tumor growth in some glioblastoma cells. SCP1-IN-2 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity.

For research use only. We do not sell to patients.

SCP1-IN-2 Chemical Structure

SCP1-IN-2 Chemical Structure

CAS No. : 2764615-56-5

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Description

SCP1-IN-2 (Compound SH T-65) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-2 promotes REST degradation and reduces transcriptional activity. A high level of REST protein drives the tumor growth in some glioblastoma cells. SCP1-IN-2 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity[1].

Molecular Weight

490.47

Formula

C19H17F3N2O6S2

CAS No.
SMILES

O=S1(C2=CC=CC=C2C=C1C(NCCCNS(C3=CC=C(C=C3)OC(F)(F)F)(=O)=O)=O)=O

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SCP1-IN-2
Cat. No.:
HY-142683
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