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Il36a

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  • HY-P70702
    IL-36 alpha/IL-1F6 Protein, Human

    Il-36 alpha; Il-36α; Interleukin-36 Alpha; FIl1 EpsIlon; Interleukin-1 EpsIlon; Il-1 EpsIlon; Interleukin-1 FamIly Member 6; Il-1F6; Il36a; FIl1E; Il1E; Il1F6

    		 Human E. coli
    IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-κB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP. IL-36 alpha/IL-1F6 Protein, Human is a recombinant human IL-36 alpha without any tag, which is produced in E. coli.
  • HY-P700126AF
    Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His)

    Il-36 alpha; Il-36α; Interleukin-36 Alpha; FIl1 EpsIlon; Interleukin-1 EpsIlon; Il-1 EpsIlon; Interleukin-1 FamIly Member 6; Il-1F6; Il36a; FIl1E; Il1E; Il1F6

    		 Human E. coli
    IL-36 α/IL-1F6 protein binds to IL1RL2/IL-36R receptor, activates NF-kappa-B and MAPK pathways, and induces pro-inflammatory responses. IL-36 α/IL-1F6 also upregulates CD83, CD86, and HLA-DR in dendritic cells, promotes dendritic cell maturation, and drives T cell proliferation. Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His) is the recombinant human-derived animal-FreeIL-36 alpha/IL-1F6 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-36 alpha/IL-1F6 Protein, Human (His) is 153 a.a., with molecular weight of ~18.05 kDa.This product is for cell culture use only.

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