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α-Galactosidase A

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Endogenous Metabolite (2) Fluorescent Dye (1)
By Research Areas:	Metabolic Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

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Products

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2871

α-Galactosidase, Aspergillus niger EC 3.2.1.22	Endogenous Metabolite	Others
α-Galactosidase, Aspergillus niger (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides .

HY-14929A

Migalastat hydrochloride GR181413A	Others	Others
Migalastat hydrochloride (GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC₅₀ of 0.04 μM for human α-Gal A.

HY-118135

4-Methylumbelliferyl-α-D-galactopyranoside 4MU-α-Gal	Fluorescent Dye	Others
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .

HY-N7088

Raffinose 1 Publications Verification Melitose	Endogenous Metabolite	Metabolic Disease
Raffinose (Melitose), a non-digestible short-chain oligosaccharide, is a trisaccharide composed of galactose, glucose, and fructose and can be found in many plants. Raffinose (Melitose) can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL) .

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Biochemical Assay Reagents	Others
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates .

HY-14929

Migalastat GR181413A free base	Others	Others
Migalastat (GR181413A free base) is an orally active and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC₅₀ of 0.04 μM for human α-Gal A .

Cat. No.	Product Name	Type

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Enzyme Substrates
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates .

HY-E70180

α-Galactosidase A EC:3.2.1.22; GLA	Enzyme Substrates
alpha-Galactosidase A is a lysosomal exoglycosidase and hydrolyses the terminal α-galactosyl moieties of glycoconjugates .

HY-123000

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside	Enzyme Substrates
4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside

Enzyme Substrates

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.

HY-W089785

Methyl α-D-galactopyranoside monohydrate	Carbohydrates
Methyl α-D-galactopyranoside monohydrate is an alpha-D-galactoside having a methyl substituent at the anomeric position. Methyl α-D-galactopyranoside inhibits debaryomyces hansenii UFV-1 extracellular and intracellular *α-galactosidases* with K_i values of 0.82 and 1.12 mM, respectively .

Raffinose 1 Publications Verification Melitose	Structural Classification Human Gut Microbiota Metabolites Polysaccharides other families Microorganisms Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
Raffinose (Melitose), a non-digestible short-chain oligosaccharide, is a trisaccharide composed of galactose, glucose, and fructose and can be found in many plants. Raffinose (Melitose) can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL) .

Species:	Human (1) Mouse (1)
Tag:	His (2)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P73077

	*GLA/alpha-Galactosidase* A Protein, Mouse (HEK293, His)** Alpha-Galactosidase A; GALA; GLA; Melibiase	Mouse	HEK293
	GLA/alpha-Galactosidase A Protein is responsible for the breakdown of alpha-galactoside in the lysosome. GLA/alpha-Galactosidase A Protein participates in the negative regulation of nitric oxide biosynthesis and nitric oxide synthase activity. A deficiency of GLA/alpha-Galactosidase A Protein causes Fabry disease. GLA/alpha-Galactosidase A Protein, Mouse (HEK293, His) is the recombinant mouse-derived GLA/alpha-Galactosidase A protein, expressed by HEK293, with C-His labeled tag. The total length of GLA/alpha-Galactosidase A Protein, Mouse (HEK293, His) is 388 a.a., with molecular weight of 46-52 kDa.

HY-P7492

	Alpha-Galactosidase A Protein, Human (HEK293, His) rHualpha-Galactosidase A, His; GLA; alpha-Galactosidase A	Human	HEK293
	Alpha-Galactosidase A Protein, Human (HEK293, His), a recombinant human alpha-Galactosidase A produced in HEK293 cells, has a His tag at the C-terminus. Alpha-Galactosidase A Protein, Human (HEK293, His) is the lysosomal exoglycosidase responsible for the hydrolysis of terminal α-galactosyl residues from glycoconjugates and is the defective enzyme causing Fabry disease.

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