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Results for "

1,4-Dihydropyridine

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19664
    Pranidipine

    OPC-13340

    		 Calcium Channel Cardiovascular Disease
    Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity .
    Pranidipine
  • HY-118594
    Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate

    		Others Metabolic Disease
    Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a mouse-modeling drug that can induce Mallory body (MB) formation. MBs reached maximum concentration on day 5 of refeeding. Liver cell regeneration increased on the third day of refeeding .
    Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • HY-135218A
    AV-153 free base
    1 Publications Verification

    		 DNA/RNA Synthesis Cancer
    AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity .
    AV-153 free base
  • HY-169333
    1,4-Dihydropyridine

    1,4-DHP

    		 Calcium Channel Cardiovascular Disease
    1,4-Dihydropyridine is an inhibitor for calcium channel, that blocks the L-type calcium channels, reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, and thus reduces the contractility and heart rate of the heart, dilates blood vessels, and lowers blood pressure .
    1,4-Dihydropyridine
  • HY-U00034
    PCA50941

    		Others Cardiovascular Disease
    PCA50941 is a 1,4-dihydropyridine derivative, used for treatment for cardiovascular disease.
    PCA50941
  • HY-W267959
    Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

    		Drug Derivative Others
    Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is a pyridine derivative that can be synthesized by the reaction of benzaldehyde, ethyl acetoacetate and NH4HCO3 .
    Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate
  • HY-106808
    Cerebrocrast

    IOS-1.1212

    		 Calcium Channel Chloride Channel Neurological Disease
    Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties .
    Cerebrocrast
  • HY-135218
    AV-153

    		DNA/RNA Synthesis Cancer
    AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity .
    AV-153

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