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ADP-ribosylation factor

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By Targets:	Adenylate Cyclase (1) Enterovirus (2) Phospholipase (1) Ras (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (3) Endocrinology (1) Infection (2)

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

6

Recombinant Proteins

2

Antibodies

Targets Recommended: Arf Family GTPase Poly(ADP-ribose) Glycohydrolase (PARG) PARP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

QS11 1 Publications Verification	β-catenin Wnt	Cancer
QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC₅₀ of 1.5 μM. QS11 activates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells .

Golgicide A Maximum Cited Publications 6 Publications Verification GCA	Enterovirus	Infection Cancer
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

NAV-2729 Maximum Cited Publications 6 Publications Verification	Ras	Cancer
NAV-2729 is a dual Arf1/Arf6 activation inhibitor. ADP ribosylation factors (Arfs) are members of the Arf family of GTP-binding proteins of the Ras superfamily.

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Adenylate Cyclase	Endocrinology
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

(Rac)-Golgicide A (Rac)-GCA	Enterovirus	Infection
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

1-Palmitoyl-2-stearoyl-rac-glycerol DG(16:0/18:0/0:0); 1-Palmitin-2-Stearin	Others	Others
1-Palmitoyl-2-stearoyl-rac-glycerol (DG(16:0/18:0/0:0)) is a compound mentioned in the study of the activation of ADP-ribosylation factor 1 GTPase activating protein by phosphatidylcholine-derived diacylglycerol, and related studies have shown that it may be involved in certain feedback mechanisms within cells.

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

Cat. No.	Product Name	Type

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Gene Sequencing and Synthesis
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

Cat. No.	Product Name	Target	Research Area

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

Species:	Human (6)
Tag:	His (4) Myc (1) GST (2) Fc (1)
Source:	HEK293 (1) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

	ARF5 Protein, Human (His) ADP-ribosylation factor 5; ARF5	Human	E. coli
	ARF5 Protein, Human (His) is the recombinant human-derived ARF5 protein, expressed by E. coli , with N-His labeled tag. The total length of ARF5 Protein, Human (His) is 180 a.a., with molecular weight of ~23 kDa.

	ARF3 Protein, Human (His) ADP-ribosylation factor 3; ARF3	Human	E. coli
	ARF3 protein, a GTP-binding allosteric activator of cholera toxin, plays a role in protein trafficking and vesicle dynamics in the Golgi apparatus. Beyond toxin activation, ARF3 interacts with PRKCABP, participating in diverse cellular processes. It also associates with PI4KB and NCS1/FREQ at the Golgi complex, emphasizing its role in crucial molecular interactions for cellular functions. ARF3 Protein, Human (His) is the recombinant human-derived ARF3 protein, expressed by E. coli , with N-His labeled tag. The total length of ARF3 Protein, Human (His) is 181 a.a., with molecular weight of ~23 kDa.

	ARF1 Protein, Human (His-GST, Myc) ADP ribosylation factor 1; ADP-ribosylation factor 1; ARF 1; ARF1; ARF1_HUMAN	Human	E. coli
	ARF1 is a small GTPase responsible for coordinating protein transport within the Golgi complex. In its GTP-bound state, ARF1 critically regulates Golgi vesicle budding and uncoating by recruiting coat proteins. ARF1 Protein, Human (His-GST, Myc) is the recombinant human-derived ARF1 protein, expressed by E. coli , with N-10*His, C-Myc, GST labeled tag. The total length of ARF1 Protein, Human (His-GST, Myc) is 180 a.a., with molecular weight of ~55 kDa.

	ARL6IP6 Protein, Human (HEK293, Fc) ADP-ribosylation factor-like protein 6-interacting protein 6; Aip-6; PFAAP1	Human	HEK293
	ARL6IP6 Protein is present in the inner nuclear membrane and displays transmembrane characteristics. ARL6IP6 gene plays a role in the activation of NF-κB and in the regulation of cell growth and apoptosis. ARL6IP6 can be used in research of cutis marmorata telangiectatica (CMTC). ARL6IP6 Protein, Human (HEK293, Fc) is the recombinant human-derived ARL6IP6 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of ARL6IP6 Protein, Human (HEK293, Fc) is 110 a.a., with molecular weight of ~34-53 KDa.

	ARL2BP Protein, Human (His) ADP ribosylation factor like 2 binding protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (His) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-6*His labeled tag.

	ARL2BP Protein, Human (GST) ADP ribosylation factor like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ARL2BP protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (GST) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-GST labeled tag.

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	ARF6 Antibody (YA3016) ADP ribosylation factor 6; ARF6; Small GTP binding protein	WB, ICC/IF	Human, Mouse, Rat
	ARF6 Antibody (YA3016) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3016), targeting ARF6, with a predicted molecular weight of 20 kDa. ARF6 Antibody (YA3016) can be used for WB, ICC/IF experiment in human, mouse, rat background.

	ARF5 Antibody (YA2836) ADP ribosylation factor 5; Arf5	WB, FC	Human, Mouse, Rat
	ARF5 Antibody (YA2836) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2836), targeting ARF5, with a predicted molecular weight of 21 kDa (observed band size: 18 kDa). ARF5 Antibody (YA2836) can be used for WB, FC experiment in human, mouse, rat background.

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