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ADP-ribosylation factor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (1) Enterovirus (2) Phospholipase (1) VEGFR (1)
By Research Areas:	Cancer (3) Endocrinology (1) Infection (2)

6

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

6

Recombinant Proteins

2

Antibodies

Targets Recommended: Poly(ADP-ribose) Glycohydrolase (PARG) PARP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

QS11 1 Publications Verification	Others	Cancer
QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC₅₀ of 1.5 μM. QS11 modulates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells .

Golgicide A 4 Publications Verification GCA	Enterovirus	Infection Cancer
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Adenylate Cyclase	Endocrinology
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

(Rac)-Golgicide A (Rac)-GCA	Enterovirus	Infection
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

M-COPA AMF-26	VEGFR	Cancer
M-COPA (AMF-26) is an inhibitor of ADP ribosylation factor 1 (Arf1)-mediated vesicle transport. M-COPA disrupts the structure of the Golgi apparatus, inhibits the processing and transport of receptor tyrosine kinases (RTKs) to the cell surface and extracellular space, thereby exerting antitumor activity against RTK-addicted cancers .

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

Cat. No.	Product Name	Type

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Gene Sequencing and Synthesis
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

Cat. No.	Product Name	Target	Research Area

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

Species:	Human (6)
Tag:	His (4) Myc (1) GST (2) Fc (1)
Source:	HEK293 (1) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

	ARF5 Protein, Human (His) ADP-ribosylation factor 5; ARF5	Human	E. coli

	ARF3 Protein, Human (His) ADP-ribosylation factor 3; ARF3	Human	E. coli
	ARF3 protein, a GTP-binding allosteric activator of cholera toxin, plays a role in protein trafficking and vesicle dynamics in the Golgi apparatus. Beyond toxin activation, ARF3 interacts with PRKCABP, participating in diverse cellular processes. It also associates with PI4KB and NCS1/FREQ at the Golgi complex, emphasizing its role in crucial molecular interactions for cellular functions. ARF3 Protein, Human (His) is the recombinant human-derived ARF3 protein, expressed by E. coli , with N-His labeled tag. The total length of ARF3 Protein, Human (His) is 181 a.a., with molecular weight of ~23 kDa.

	ARF1 Protein, Human (His-GST, Myc) ADP ribosylation factor 1; ADP-ribosylation factor 1; ARF 1; ARF1; ARF1_HUMAN	Human	E. coli
	ARF1 is a small GTPase responsible for coordinating protein transport within the Golgi complex. In its GTP-bound state, ARF1 critically regulates Golgi vesicle budding and uncoating by recruiting coat proteins. ARF1 Protein, Human (His-GST, Myc) is the recombinant human-derived ARF1 protein, expressed by E. coli , with N-10*His, C-Myc, GST labeled tag. The total length of ARF1 Protein, Human (His-GST, Myc) is 180 a.a., with molecular weight of ~55 kDa.

	ARL6IP6 Protein, Human (HEK293, Fc) ADP-ribosylation factor-like protein 6-interacting protein 6; Aip-6; PFAAP1	Human	HEK293

	ARL2BP Protein, Human (His) ADP ribosylation factor like 2 binding protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (His) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-6*His labeled tag.

	ARL2BP Protein, Human (GST) ADP ribosylation factor like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ARL2BP protein; BART; BART1; Binder of ARF2 protein 1	Human	E. coli
	The ARL2BP protein cooperates with ARL2 to play a crucial role in the nuclear translocation, retention, and transcriptional activity of STAT3, highlighting its cellular involvement. As a potential effector of ARL2, ARL2BP forms a complex with ARL2, SLC25A6, and ARL3. ARL2BP Protein, Human (GST) is the recombinant human-derived ARL2BP protein, expressed by E. coli , with N-GST labeled tag.

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	ARF5 Antibody (YA2836) ADP ribosylation factor 5; Arf5	WB, FC	Human, Mouse, Rat
	ARF5 Antibody (YA2836) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2836), targeting ARF5, with a predicted molecular weight of 21 kDa (observed band size: 18 kDa). ARF5 Antibody (YA2836) can be used for WB, FC experiment in human, mouse, rat background.

	ARF6 Antibody (YA3016) ADP ribosylation factor 6; ARF6; Small GTP binding protein	WB, ICC/IF	Human, Mouse, Rat
	ARF6 Antibody (YA3016) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3016), targeting ARF6, with a predicted molecular weight of 20 kDa. ARF6 Antibody (YA3016) can be used for WB, ICC/IF experiment in human, mouse, rat background.

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