Search Result
Results for "
ALD
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-130107
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC).
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-
-
- HY-130496
-
|
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PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
-
- HY-130099
-
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ADC Linker
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Cancer
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Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate .
|
-
-
- HY-133426
-
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ALD-benzyl-amide-PEG4-propargyl
|
ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-136127
-
|
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ADC Linker
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Cancer
|
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ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
-
- HY-136309
-
|
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ADC Linker
|
Cancer
|
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Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
-
- HY-140628
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140629
-
|
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PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140626
-
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PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
-
- HY-140624
-
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-PEG12-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
-
- HY-140625
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-PEG24-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140623
-
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PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
-
- HY-140627
-
|
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PROTAC Linkers
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Cancer
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Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140622
-
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PROTAC Linkers
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Cancer
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Ald-Ph-amido-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130096
-
|
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ADC Linker
|
Cancer
|
|
Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative, used as a noncleavable ADC linker .
|
-
-
- HY-130527
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140636
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140631
-
|
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PROTAC Linkers
|
Cancer
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Ald-CH2-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140630
-
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PROTAC Linkers
|
Cancer
|
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Ald-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130144
-
|
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ADC Linker
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Ald-CH2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-130098
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used for the antibody-drug conjugate (ADC).
|
-
-
- HY-130758
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-PEG1-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130330
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
-
- HY-130962
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG23-OPSS is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
-
- HY-130097
-
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ADC Linker
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Cancer
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Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).
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-
-
- HY-133579
-
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
-
- HY-140635
-
|
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PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-130154
-
|
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PROTAC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133572
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
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- HY-130100
-
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ADC Linker
|
Cancer
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Ald-Ph-amido-PEG3-C1-Boc is an ADC linker, which belongs to a polyethylene glycol (PEG) linker.
|
-
-
- HY-140634
-
|
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ADC Linker
|
Cancer
|
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Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-130967
-
|
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ADC Linker
|
Cancer
|
|
Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-130102
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG3-C2-Pfp ester is an noncleavable ADC linker, which belongs to a polyethylene glycol (PEG) linker.
|
-
-
- HY-130202
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140632
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-amido-C2-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130974
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
-
- HY-130105
-
|
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ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG1-C2-Pfp ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
-
- HY-130106
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG1-C2-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
-
- HY-130101
-
|
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ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
-
- HY-130103
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
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- HY-130104
-
|
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ADC Linker
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Cancer
|
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Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
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- HY-130669
-
|
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PROTAC Linkers
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Cancer
|
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Ald-Ph-amido-C2-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
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- HY-130667
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-Ph-amido-C2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-130174
-
|
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PROTAC Linkers
|
Cancer
|
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Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130770
-
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PROTAC Linkers
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Cancer
|
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Ald-CH2-PEG3-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of SGK3 kinase PROTAC degrader .
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-
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- HY-133546
-
|
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ADC Linker
|
Cancer
|
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Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
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- HY-130969
-
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ADC Linker
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Cancer
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Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
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- HY-140633
-
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N3-PEG4-CH2CH2CHO
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PROTAC Linkers
|
Cancer
|
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Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-C2-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
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- HY-132092
-
|
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PROTAC Linkers
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Cancer
|
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Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
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- HY-N12909
-
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Z9,E12-14:ALD
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Others
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Endocrinology
|
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(Z,E)-9,12-Tetradecadienal (Z9,E12-14:Ald) is a female pheromone that can induce an electroantennographic response in male antennae, isolated from the sex pheromone extracts of Plodia interpunctella (lepidoptera: pyralidae) .
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- HY-131086
-
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- HY-W440884
-
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Biochemical Assay Reagents
|
Others
|
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DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
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- HY-145122
-
|
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Others
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Metabolic Disease
|
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ELOVL1-IN-1 is an ELOVL1 inhibitor extracted from patent WO2018107056A1, compound 87. ELOVL1-IN-1 can reduce very long chain fatty acid levels. ELOVL1-IN-1 can be used for the research of adrenoleukodystrophy (ALD) .
|
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- HY-W440885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-145272
-
|
|
ELOVL
|
Neurological Disease
|
|
ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD) [1].
|
-
- HY-W440883
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W439487
-
|
|
Others
|
Metabolic Disease
|
|
7,9-Dimethylguanine is a modified nucleotide base whose content in urine and serum of patients with alcoholic liver disease (ALD) is closely related to the severity of ALD. The free nucleotides/bases in urine and serum samples of ALD patients and controls were extracted and quantified by untargeted and nontargeted metabolomics methods, and 39 free nucleotides/bases were found in urine and 40 in serum, of which 12 and 11 modified nucleotide bases were significantly changed in patient samples (q < 0.05 and fold-change > 20%). The content of 7,9-Dimethylguanine in urine and 2-methylthio-N6-serine carbamoyl adenosine (ms2t6A) in serum were strongly associated with the severity of ALD, with Spearman rank correlation coefficients of 0.66 and 0.74 with Model for End-stage Liver Disease (MELD) scores, respectively. Notably, the levels of these two metabolites varied sufficiently to distinguish severe alcoholic hepatitis (AH) from non-severe ALD, and non-severe ALD from healthy controls.
|
-
- HY-N12939
-
|
|
Others
|
Endocrinology
|
|
(11Z,13Z)-Hexadecadien-1-ol is an insect sex pheromone attractive to male navel orangeworm moths (Amyeloistransitella), a secretion of the moth Z11, which can be isolated from Z13-16:Ald analogs .
|
-
- HY-113301
-
-
- HY-145270
-
|
|
Others
|
Metabolic Disease
|
|
ELOVL1-IN-2 is an elongation of very long chain fatty acid 1 (ELOVL1) enzyme inhibitor, ELOVL1-IN-2 shows weak ELOVL1 inhibition (IC50=21 μM) and moderate potency in a primary cellular assay (HEK293 C26 IC50=6.7 μM) .
|
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- HY-113301S1
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Hexacosanoic acid-d4-11 is the deuterium labeled Hexacosanoic acid. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
|
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- HY-113301R
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Hexacosanoic acid (Standard) is the analytical standard of Hexacosanoic acid. This product is intended for research and analytical applications. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
|
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- HY-113301S
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Hexacosanoic acid-d4 is the deuterium labeled Hexacosanoic acid[1]. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis[2].
|
-
- HY-45854
-
GWP-042
1 Publications Verification
|
Bacterial
|
Infection
|
|
GWP-042 is a potent inhibitor of mycobacterial alanine dehydrogenase (Ald) Rv2780, with the IC50 of 0.21 μM. GWP-042 has antimicrobial activity against M. tuberculosis infection in vivo .
|
-
- HY-156679
-
|
|
Thyroid Hormone Receptor
|
Neurological Disease
|
|
VK-0214 is an agonist for thyroid beta receptor (TRβ), which ameliorates the X-linked adrenoleukodystrophy (X-ALD), through activation of ABCD2 expression and reduction of very long chain fatty acids (VLCFA) accumulation .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W440884
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W440885
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113301S1
-
|
|
|
Hexacosanoic acid-d4-11 is the deuterium labeled Hexacosanoic acid. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
|
-
-
- HY-113301S
-
|
|
|
Hexacosanoic acid-d4 is the deuterium labeled Hexacosanoic acid[1]. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis[2].
|
-
| Cat. No. |
Product Name |
|
Classification |
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- HY-130667
-
|
|
|
PROTAC Synthesis
Azide
|
|
Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-Ph-amido-C2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133426
-
|
ALD-benzyl-amide-PEG4-propargyl
|
|
ADC Synthesis
Alkynes
|
|
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130144
-
|
|
|
Azide
PROTAC Synthesis
ADC Synthesis
|
|
Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Ald-CH2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140635
-
|
|
|
Azide
PROTAC Synthesis
|
|
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140634
-
|
|
|
Azide
ADC Synthesis
|
|
Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130967
-
|
|
|
ADC Synthesis
Alkynes
|
|
Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130974
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Tetrazine
ADC Synthesis
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Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130969
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Azide
ADC Synthesis
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Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140633
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N3-PEG4-CH2CH2CHO
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Azide
PROTAC Synthesis
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Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-C2-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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| Cat. No. |
Product Name |
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Classification |
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- HY-W440883
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Pegylated Lipids
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DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
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