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Results for "

Adefovir

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1826
    Adefovir
    1 Publications Verification

    GS-0393; PMEA

    		 HBV Reverse Transcriptase Infection
    Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .
    Adefovir
  • HY-B0255
    Adefovir dipivoxil
    1 Publications Verification

    GS 0840

    		 HBV Reverse Transcriptase Orthopoxvirus Endogenous Metabolite Infection Cancer
    Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains . Adefovir dipivoxil shows anti-orthopoxvirus activity.
    Adefovir dipivoxil
  • HY-108917
    Morphothiadin
    5 Publications Verification

    GLS4

    		 HBV Infection
    Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC50 of 12 nM.
    Morphothiadin
  • HY-B0255R
    Adefovir dipivoxil (Standard)

    		HBV Reverse Transcriptase Orthopoxvirus Endogenous Metabolite Infection Cancer
    Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains . Adefovir dipivoxil shows anti-orthopoxvirus activity.
    Adefovir dipivoxil (Standard)
  • HY-168165
    Adefovir diphosphate

    		Others Cancer
    Adefovir diphosphate is an antiviral compound with activity against hepatitis B virus (HBV). Adefovir diphosphate blocks the replication of HBV by inhibiting reverse transcriptase. Adefovir diphosphate has also shown activity against other viruses such as herpes viruses and human immunodeficiency virus. Adefovir diphosphate is used as an effective inhibitory option in the suppression of chronic hepatitis B. The mechanism of action of Adefovir diphosphate involves blocking the autophosphorylation of growth factor receptors, thereby potentially reducing the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B .
    Adefovir diphosphate

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