Search Result
Results for "
Angelica
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N6929
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Others
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Neurological Disease
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Angelic Acid is a substance found in Angelica sinensis, and it exists in an ester form. Angelic acid aids in wound healing and exhibits psychotropic properties .
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- HY-N0548
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Glutathione S-transferase
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Cancer
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α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .
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- HY-N1286
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3-Hydroxysenkyunolide A
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Others
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Others
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Senkyunolide G (3-Hydroxysenkyunolide A) is a natural product that can be isolated from Angelica sinensis .
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- HY-N13219
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Others
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Metabolic Disease
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Angelica Extract is an angelica extract, and its components include: Ligustilide. Angelica Extract can effectively inhibit the differentiation of osteoclasts, regulate osteoclastogenesis and/or bone loss. Angelica Extract has the potential to be used in the study of various bone diseases caused by excessive bone resorption. .
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- HY-N0401B
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- HY-N12069
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Others
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Inflammation/Immunology
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Praeroside IV can be isolated from the roots of Angelica furcijuga. Praeroside IV can be used for research of D-GalN/LPS-induced liver injury .
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- HY-N1527
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Quinovic acid 3-O-α-L-rhamnoside
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Others
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Others
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Quinovic acid 3-O-α-L-rhamnopyranoside (Quinovic acid 3-O-α-L-rhamnoside) is glycoside derivative. Quinovic acid 3-O-α-L-rhamnopyranoside can be isolated from the root bark of Guettarda angelica .
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- HY-N9507
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Apoptosis
FGFR
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Cancer
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Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .
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- HY-N12070
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Others
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Cardiovascular Disease
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11-O-β-D-glucopyranosyl thamnosmonin, a coumarin glucosides, can be isolated from the roots of Angelica apaensis. 11-O-β-D-glucopyranosyl thamnosmonin has weak inhibitory activity on the aggregation of rabbit platelets induced by PAF, AA, and ADP .
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- HY-N9535A
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Drug Metabolite
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Metabolic Disease
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(R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis .
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- HY-N9364
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Others
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Others
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Iso-oxypeucedanin is a coumarin found in Angelica dahurica.
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- HY-N4234
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- HY-N4273
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(±)-Heraclenin
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Others
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Others
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Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
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- HY-N3524
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- HY-N2272
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- HY-134573
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Others
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Others
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Dihydropashanone is a Chalcones product that can be isolated from the roots of Angelica pubescens .
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- HY-126754
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- HY-N4052
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Bacterial
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Infection
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Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities .
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- HY-N0947
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(-)-Praeruptorin B
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Others
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Inflammation/Immunology
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(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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- HY-N4052A
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Bacterial
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Infection
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(±)-Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities .
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- HY-N8923
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Others
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Others
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Angelol H is a natural tcompound isolated from Angelica pubescens MAXIM. (Umbelliferae) .
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- HY-N1350
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Others
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Others
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Riligustilide (compound 2) is a kind of phthalide dimer. Riligustilide can be isolated from the radix of Angelica sinensis .
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- HY-N2623
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Prangenidin
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Others
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Cancer
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Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity .
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- HY-N0286
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- HY-N2488
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7-Demethylsuberosin
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Others
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Inflammation/Immunology
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Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity .
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- HY-N7034
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Others
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Neurological Disease
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Magnolioside, isolated from Angelica gigas Nakai (Umbelliferae), exhibits significant neuroprotective activities against glutamate-induced toxicity .
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- HY-N0075
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Others
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Metabolic Disease
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(Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM .
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- HY-N4273R
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Others
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Others
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Oxyimperatorin (Standard) is the analytical standard of Oxyimperatorin. This product is intended for research and analytical applications. Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
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- HY-N0825
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- HY-N2414
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Others
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Inflammation/Immunology
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Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation .
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- HY-N2276
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Others
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Inflammation/Immunology
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Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic .
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- HY-N4109
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Others
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Inflammation/Immunology
Cancer
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Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity .
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- HY-W099617
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1-Decanoyl-rac-glycerol
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Others
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Others
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2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a natural product that can be isolated from the root of Angelica dahurica .
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- HY-N4236
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Others
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Others
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Angelol A is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
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- HY-N4322
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PKC
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Inflammation/Immunology
Cancer
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Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities .
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- HY-N0947R
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Others
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Inflammation/Immunology
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(-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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- HY-N0401
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- HY-N0708
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- HY-N4235
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Others
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Inflammation/Immunology
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Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
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- HY-N6892
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Others
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Cancer
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3'-O-Acetylhamaudol, isolated from Angelica polymorpha, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation .
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- HY-N9532
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Anhydrobyakangelicin
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Others
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Cancer
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Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC50s of 70.04 μM and 17.97 μM .
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- HY-N8856
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Others
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Others
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Angelol M,isolated from the roots of Angelica gigas Nakai, shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells .
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- HY-N0286R
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Cholinesterase (ChE)
Bacterial
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Neurological Disease
Cancer
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Isoimperatorin (Standard) is the analytical standard of Isoimperatorin. This product is intended for research and analytical applications. Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
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- HY-111588
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- HY-N2110
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Akt
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Inflammation/Immunology
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Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium .
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- HY-N0825R
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Cholinesterase (ChE)
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Inflammation/Immunology
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Nodakenin (Standard) is the analytical standard of Nodakenin. This product is intended for research and analytical applications. Nodakenin is a major coumarin glucoside in the root of Angelica decusiva. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM .
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- HY-N8414
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- HY-N0377A
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(±)-4',7-Dihydroxyflavanone
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Reactive Oxygen Species
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Cardiovascular Disease
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(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is isolated from Angelica keiskei, a hardy perennial herb of the Umbelliferae family. (±)-Liquiritigenin promotes cell proliferation, has cytoprotective activity and reduces cytotoxicity, and also has antioxidant stress effects .
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- HY-N0075R
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Others
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Metabolic Disease
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(Rac)-Byakangelicin (Standard) is the analytical standard of (Rac)-Byakangelicin. This product is intended for research and analytical applications. (Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM .
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- HY-N4109R
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Others
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Inflammation/Immunology
Cancer
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Decursinol (Standard) is the analytical standard of Decursinol. This product is intended for research and analytical applications. Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity .
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- HY-N8366
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Phosphatase
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Endocrinology
Cancer
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Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC50 of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .
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- HY-148937
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PI3K
Akt
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Others
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Oroselol is a coumarin commonly found in a variety of plants, especially in the roots of angelica plants and the bark of cinnamon trees. Oroselol has potential medicinal properties, including anti-inflammatory, antioxidant and anti-tumor effects. Oroselol can be used in the production of fragrances, flavors and medicines
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- HY-N0708R
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NF-κB
Bacterial
Endogenous Metabolite
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Infection
Inflammation/Immunology
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Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .
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- HY-N4322R
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PKC
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Inflammation/Immunology
Cancer
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Decursinol angelate (Standard) is the analytical standard of Decursinol angelate. This product is intended for research and analytical applications. Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities .
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- HY-N10856
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Others
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Others
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6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source .
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- HY-W778225
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Isotope-Labeled Compounds
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Infection
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Vanillic acid- 13C6 is the 13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
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- HY-N2110R
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Akt
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Inflammation/Immunology
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Phellopterin (Standard) is the analytical standard of Phellopterin. This product is intended for research and analytical applications. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium .
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- HY-W087444A
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Bacterial
Antibiotic
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Infection
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(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities .
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- HY-N2554
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Ostenol
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Monoamine Oxidase
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Neurological Disease
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Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B .
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- HY-165044
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DG(18:3/0:0/18:3); 1,3-Dilinolenin
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Others
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Others
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1,3-Di-α-linolenoyl glycerol (DG(18:3/0:0/18:3)) is a compound mentioned in the study of the chemical composition of Angelica acutiloba root. A variety of compounds have been isolated from the root, some of which have affinity for 5-HT(7) receptors.
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- HY-N0747
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Potassium Channel
Apoptosis
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Cardiovascular Disease
Cancer
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Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation . Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration .
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- HY-N0074
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COX
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Inflammation/Immunology
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Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory agent on airway inflammation .
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- HY-N6022
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Others
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Metabolic Disease
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Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects . Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of agent-agent interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones .
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- HY-N0747R
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Potassium Channel
Apoptosis
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Cardiovascular Disease
Cancer
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Oxypeucedanin (Standard) is the analytical standard of Oxypeucedanin. This product is intended for research and analytical applications. Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM.?Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation . Oxypeucedanin induces cell?apoptosis through inhibition of cancer cell migration .
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- HY-N7204
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Monoamine Oxidase
Dopamine β-hydroxylase
Apoptosis
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Neurological Disease
Inflammation/Immunology
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4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-W778225
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Vanillic acid- 13C6 is the 13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
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