2,3-Dihydroxypropyl decanoate (Synonyms: 1-Decanoyl-rac-glycerol)

Cat. No.: HY-W099617 Purity: 99.92%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a natural product that can be isolated from the root of Angelica dahurica.

For research use only. We do not sell to patients.

2,3-Dihydroxypropyl decanoate Chemical Structure

CAS No. : 2277-23-8

Size	Stock	Quantity
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Other Forms of 2,3-Dihydroxypropyl decanoate:

2,3-Dihydroxypropyl decanoate-d5 Get quote

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Description

2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a natural product that can be isolated from the root of Angelica dahurica^[1].

Molecular Weight

246.34

Formula

C₁₃H₂₆O₄

CAS No.

2277-23-8

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCC(=O)OCC(CO)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (405.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.0594 mL	20.2972 mL	40.5943 mL
5 mM	0.8119 mL	4.0594 mL	8.1189 mL
10 mM	0.4059 mL	2.0297 mL	4.0594 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.92%

Select Batch:

Data Sheet (266 KB) SDS (393 KB)

COA (240 KB) HNMR (258 KB) RP-HPLC (131 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Liu D, et al. Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6833-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.0594 mL	20.2972 mL	40.5943 mL	101.4858 mL
	5 mM	0.8119 mL	4.0594 mL	8.1189 mL	20.2972 mL
	10 mM	0.4059 mL	2.0297 mL	4.0594 mL	10.1486 mL
	15 mM	0.2706 mL	1.3531 mL	2.7063 mL	6.7657 mL
	20 mM	0.2030 mL	1.0149 mL	2.0297 mL	5.0743 mL
	25 mM	0.1624 mL	0.8119 mL	1.6238 mL	4.0594 mL
	30 mM	0.1353 mL	0.6766 mL	1.3531 mL	3.3829 mL
	40 mM	0.1015 mL	0.5074 mL	1.0149 mL	2.5371 mL
	50 mM	0.0812 mL	0.4059 mL	0.8119 mL	2.0297 mL
	60 mM	0.0677 mL	0.3383 mL	0.6766 mL	1.6914 mL
	80 mM	0.0507 mL	0.2537 mL	0.5074 mL	1.2686 mL
	100 mM	0.0406 mL	0.2030 mL	0.4059 mL	1.0149 mL

2,3-Dihydroxypropyl decanoate Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,3-Dihydroxypropyl decanoate2277-23-81-Decanoyl-rac-glycerolOthersInhibitorinhibitorinhibit

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2,3-Dihydroxypropyl decanoate (Synonyms: 1-Decanoyl-rac-glycerol)

Other Forms of 2,3-Dihydroxypropyl decanoate:

2,3-Dihydroxypropyl decanoate Related Antibodies

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•Related Screening Libraries:

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Biological Activity

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