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ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .
APOA1 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA4 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA2 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA5 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Apoa1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid), a polyunsaturated fatty acid sourced from maritime pine seed oil, gymnospermae leaves and seeds, and freshwater gastropods, has been shown to reduce high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1 when included in their diet. In vitro studies indicate that it diminishes cholesterol efflux, and when applied topically in its methyl ester form, it alleviates inflammatory processes, likely by displacing arachidonic acid from phospholipid pools and lowering concentrations of downstream inflammatory mediators such as prostaglandin E2 and leukotrienes.
C2 Dihydroceramide is a derivative of C2 Ceramide (HY-101180). C2 Dihydroceramide enhances the ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I) without causing cytotoxicity .
Lp(a)-IN-5 (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases .
Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) (Lp (a)) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a)
formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys .
APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.
Apolipoprotein KV domain (67-77) is an 11-amino acid peptide identified from the KV domain of human apolipoprotein a (ApoA) with antiangiogenic and antitumor activities. Apolipoprotein KV domain (67-77) targets the angiogenic c-Src/ERK pathway by blocking activation signals received from vascular endothelial growth factor (VEGF). Apolipoprotein KV domain (67-77) can be used in cancer research .
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .
APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .
Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro .
Apolipoprotein KV domain (67-77) is an 11-amino acid peptide identified from the KV domain of human apolipoprotein a (ApoA) with antiangiogenic and antitumor activities. Apolipoprotein KV domain (67-77) targets the angiogenic c-Src/ERK pathway by blocking activation signals received from vascular endothelial growth factor (VEGF). Apolipoprotein KV domain (67-77) can be used in cancer research .
ApoA-IV Protein plays a vital role in lipid metabolism, influencing chylomicron and VLDL secretion and catabolism. It efficiently activates lipoprotein lipase with ApoC-II and serves as a potent activator of LCAT. As a component of HDL and chylomicrons, ApoA-IV is integral to cholesterol transport and metabolism. Structurally, the protein forms homodimers, reflecting its crucial role in lipid-related processes. ApoA-IV Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived ApoA-IV protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of ApoA-IV Protein, Mouse (P.pastoris, His) is 375 a.a., with molecular weight of ~45.0 kDa.
ApoA-IV Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-IV (Apo A-IV) has a role in reverse cholesterol transport.
APOA1BP protein plays a crucial role in cellular processes by catalyzing the S- and R-type epimerization of NAD(P)HX, a protein that results from enzymatic or heat-dependent hydration. Damaged form of NAD(P)H. This catalytic activity is a prerequisite for the subsequent action of S-specific NAD(P)H hydrate dehydratase, enabling the repair of both epimers of NAD(P)HX. APOA1BP Protein, Human (HEK293, His) is the recombinant human-derived APOA1BP protein, expressed by HEK293 , with C-His labeled tag.
Apolipoprotein AV (APOA5) is primarily associated with HDL and VLDL, affecting triglyceride (TG) levels. APOA5 stimulates apo-CII lipoprotein lipase (LPL) TG hydrolysis and inhibits hepatic VLDL-TG production without affecting VLDL-apoB production. Apolipoprotein A-V/APOA5 Protein, Mouse (His) is the recombinant mouse-derived Apolipoprotein A-V/APOA5 protein, expressed by E. coli , with N-His labeled tag. The total length of Apolipoprotein A-V/APOA5 Protein, Mouse (His) is 348 a.a., with molecular weight of ~40.5 kDa.
Apolipoprotein A-I/APOA1 Protein is a secreted protein located on the outside of cell membranes and is the main structural apolipoprotein of high-density lipoprotein (HDL), playing a key role in the reverse cholesterol transport pathway. Apolipoprotein A-I/APOA1 protein interacts with the cell surface receptor SR-BI, thereby promoting dengue virus (DV) infection. Apolipoprotein A-I/APOA1 Protein can also activate sperm motility as part of the SPAP complex. Apolipoprotein A-I/APOA1 Protein has anti-inflammatory, anti-atherosclerotic, anti-apoptotic, anti-tumor, and anti-thrombotic functions. Apolipoprotein A-I/APOA1 Protein Protein, Human is made up of 267 amino acids and is expressed in Escherichia coli (E. coli).
Apolipoprotein A-I Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-I (ApoA-I), the major protein component in high-density lipoprotein (HDL), plays key roles in the Reverse Cholesterol Transport pathway. Apolipoprotein A-I is associated with dengue virus (DV) particles and enhances virus infection through SR-BI.
Apolipoprotein A-II/ApoA2 Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-II (ApoA-II) has been associated with numerous aspects of HDL metabolism, and apoA-II overexpression produces the proatherogenic phenotype.
Apolipoprotein AI plays a key role in reverse cholesterol transport, promoting cholesterol efflux from tissues and acting as a cofactor for lecithin cholesterol acyltransferase (LCAT). It forms homodimers and participates in the SPAP complex, which is essential for sperm motility, interacting with both NAXE and CLU. Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) is the recombinant human-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag.
The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is 246 a.a., with molecular weight of ~58 kDa.
The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (240a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (240a.a, HEK293, Fc) is 240 a.a., with molecular weight of 55-65 kDa.
Apolipoprotein A-II/APOA2 protein may stabilize high-density lipoprotein (HDL) structure and affect HDL metabolism through lipid association. As a monomer, APOA2 is critical for maintaining HDL integrity and function. Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-II/APOA2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) is 84 a.a., with molecular weight of 40-45 kDa.
The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-6*His labeled tag.
The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-His labeled tag.
ApoA Antibody (YA2732) is a non-conjugated IgG antibody, targeting ApoA, with a predicted molecular weight of 227 kDa (observed band size: 501 kDa). ApoA Antibody (YA2732) can be used for WB experiment in human background.
APOA1 Antibody is an unconjugated, approximately 31 kDa, rabbit-derived, anti-APOA1 monoclonal antibody. APOA1 Antibody can be used for: WB,IHC-P,ICC/IF,IP expriments in human, mouse background without labeling.
Apo AIV; ApoA 4; ApoA IV; ApoA4; Apolipoprotein A IV; Apolipoprotein A4
WB, IP
Human
ApoA4 Antibody (YA2592) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2592), targeting ApoA4, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). ApoA4 Antibody (YA2592) can be used for WB, IP experiment in human background.
APO A2; Apo AII; ApoA 2; ApoA II; ApoA2; ApoAII; Apolipoprotein A II
WB, ICC/IF, FC
Human, Rat
ApoA2 Antibody (YA1459) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1459), targeting ApoA2, with a predicted molecular weight of 11 kDa (observed band size: 11 kDa). ApoA2 Antibody (YA1459) can be used for WB, ICC/IF, FC experiment in human, rat background.
APOA1 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA4 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA2 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
APOA5 Human Pre-designed siRNA Set A contains three designed siRNAs for APOA5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Apoa1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Apoa1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
