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Aquaporin-4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aquaporin (4) PROTAC Linkers (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Inflammation/Immunology (4) Neurological Disease (2)

6

Inhibitors & Agonists

2

Peptides

4

Recombinant Proteins

2

Antibodies

Targets Recommended: Aquaporin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

AER-271 1 Publications Verification	Aquaporin	Cardiovascular Disease Neurological Disease
AER-271, a phosphonate proagent derivative of AER-270, is an *aquaporin-4* (AQP4) inhibitor for the research of acute ischemic stroke .

TGN-073	Aquaporin	Neurological Disease
TGN-073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. TGN-073 reveals an increase of up to 41% in glymphatic transport in rat brain .

HY-W008574A

TGN-020 sodium Maximum Cited Publications 15 Publications Verification	PROTAC Linkers	Inflammation/Immunology Cancer
TGN-020 sodium is a selective **Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker** that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats ^[4].

TGN-020 Maximum Cited Publications 15 Publications Verification	PROTAC Linkers	Inflammation/Immunology Cancer
TGN-020 is a selective **Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker** that can be used in the synthesis of PROTACs .TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats ^[4].

AQP4 (205-215)	Aquaporin	Inflammation/Immunology
AQP4 (205-215) is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO) .

AQP4 (205-215) TFA	Aquaporin	Inflammation/Immunology
AQP4 (205-215) TFA is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO) .

Cat. No.	Product Name	Target	Research Area

AQP4 (205-215)	Aquaporin	Inflammation/Immunology
AQP4 (205-215) is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO) .

AQP4 (205-215) TFA	Aquaporin	Inflammation/Immunology
AQP4 (205-215) TFA is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO) .

Species:	Human (2) Mouse (2)
Tag:	His (3) SUMO (1) Tag Free (1)
Source:	E. coli Cell-free (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	AQP4 Protein, Human (His-SUMO) AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4	Human	E. coli
	The AQP4 protein forms water-specific channels and is involved in brain water balance and solute transport. AQP4 Protein, Human (His-SUMO) is the recombinant human-derived AQP4 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

	AQP4 Protein, Mouse (Cell-Free) Aquaporin-4; Mercurial-insensitive water channel; MIWC; WCH4	Mouse	E. coli Cell-free
	The AQP4 protein forms water-specific channels that are critical for brain water homeostasis and lymphoid solute transport. It regulates water exchange at the blood-brain interface, promoting the influx of cerebrospinal fluid into the brain and the drainage of interstitial fluid. AQP4 Protein, Mouse (Cell-Free) is the recombinant mouse-derived AQP4 protein, expressed by E. coli Cell-free , with tag free.

	AQP4 Protein, Mouse (Cell-Free, His) Aquaporin-4; Mercurial-insensitive water channel; MIWC; WCH4	Mouse	E. coli Cell-free
	The AQP4 protein forms water-specific channels that are critical for brain water homeostasis and lymphoid solute transport. It regulates water exchange at the blood-brain interface, promoting the influx of cerebrospinal fluid into the brain and the drainage of interstitial fluid. AQP4 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived AQP4 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

	AQP4 Protein, Human (His) AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4	Human	E. coli
	The AQP4 protein forms water-specific channels and is involved in brain water balance and solute transport. AQP4 Protein, Human (His) is the recombinant human-derived AQP4, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

	Aquaporin 4 Antibody Aquaporin 4; WCH4; Mercurial-insensitive water channel; MIWC; AQP 4; AQP4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; MGC22454; MIWC; AQP4_HUMAN; Aquaporin-4; AQP-4.	WB, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	Aquaporin 4 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Aquaporin 4, with a predicted molecular weight of 36 kDa (observed band size: 34 kDa). Aquaporin 4 Antibody can be used for WB, IHC-P, IHC-F, FC, ICC/IF experiments in human, mouse, rat, pig, cow, rabbit, sheep backgrounds.

	Aquaporin 4 Antibody (YA3204) AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4	IHC-P	Human, Rat
	Aquaporin 4 Antibody (YA3204) is a non-conjugated IgG antibody, targeting Aquaporin 4. Aquaporin 4 Antibody (YA3204) can be used for IHC-P experiment in human, rat background.

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