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Results for "

Arnt

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

1

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112374
    NPAS3-IN-1

    		HIF/HIF Prolyl-Hydroxylase Neurological Disease
    NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level .
    NPAS3-IN-1
  • HY-120087
    KG-548

    		HIF/HIF Prolyl-Hydroxylase Cancer
    KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β .
    KG-548
  • HY-W012248
    KG-655

    		Aryl Hydrocarbon Receptor Others
    KG-655 is a small molecule compound that binds to the β-folded surface and internal cavity of ARNT PAS-B and interferes with its binding to the transcriptional coactivator TACC3. KG-655 can promote the homodimerization of ARNT PAS-B and has the potential to regulate multiple ARNT-mediated signaling pathways .
    KG-655
  • HY-D0932
    Sudan IV

    Solvent Red 24; C.I. 26105

    		 Fluorescent Dye Others
    Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .
    Sudan IV
  • HY-RS01011
    ARNT Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ARNT Human Pre-designed siRNA Set A contains three designed siRNAs for ARNT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARNT Human Pre-designed siRNA Set A
    ARNT Human Pre-designed siRNA Set A
  • HY-RS18908
    Arnt Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Arnt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Arnt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Arnt Mouse Pre-designed siRNA Set A
    Arnt Mouse Pre-designed siRNA Set A
  • HY-RS01012
    ARNT2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ARNT2 Human Pre-designed siRNA Set A contains three designed siRNAs for ARNT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARNT2 Human Pre-designed siRNA Set A
    ARNT2 Human Pre-designed siRNA Set A
  • HY-P10090
    Apoptin-derived peptide

    		Akt PI3K Apoptosis Cancer
    Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer .
    Apoptin-derived peptide

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