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NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level.

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NPAS3-IN-1 Chemical Structure

NPAS3-IN-1 Chemical Structure

CAS No. : 2207-44-5

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1 mg USD 94 In-stock
5 mg USD 229 In-stock
10 mg USD 373 In-stock
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Based on 1 publication(s) in Google Scholar

NPAS3-IN-1 Related Antibodies

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Description

NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].

Molecular Weight

295.36

Formula

C10H5N3O2S3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=[N+](C1=CN=C(SC2=NC3=CC=CC=C3S2)S1)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (84.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3857 mL 16.9285 mL 33.8570 mL
5 mM 0.6771 mL 3.3857 mL 6.7714 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3857 mL 16.9285 mL 33.8570 mL 84.6425 mL
5 mM 0.6771 mL 3.3857 mL 6.7714 mL 16.9285 mL
10 mM 0.3386 mL 1.6928 mL 3.3857 mL 8.4642 mL
15 mM 0.2257 mL 1.1286 mL 2.2571 mL 5.6428 mL
20 mM 0.1693 mL 0.8464 mL 1.6928 mL 4.2321 mL
25 mM 0.1354 mL 0.6771 mL 1.3543 mL 3.3857 mL
30 mM 0.1129 mL 0.5643 mL 1.1286 mL 2.8214 mL
40 mM 0.0846 mL 0.4232 mL 0.8464 mL 2.1161 mL
50 mM 0.0677 mL 0.3386 mL 0.6771 mL 1.6928 mL
60 mM 0.0564 mL 0.2821 mL 0.5643 mL 1.4107 mL
80 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0580 mL
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NPAS3-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NPAS3-IN-12207-44-5OthersNPAS3 heterodimer inhibitorInhibitorinhibitorinhibit

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