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Results for "

BMP4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Checkpoint Kinase (Chk) (1) Small Interfering RNA (siRNA) (1) TGF-beta/Smad (1) TGF-β Receptor (2) Wee1 (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1) Metabolic Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124697

BMP signaling agonist sb4 4 Publications Verification	TGF-β Receptor	Cancer
BMP signaling agonist sb4 is a potent benzoxazole *bone morphogenetic protein 4 (BMP4) signaling* agonist with a EC₅₀ value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding, Id1 and Id3) canonical BMP signaling .

HY-18961

PD 407824	Checkpoint Kinase (Chk) Wee1	Inflammation/Immunology Cancer
PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC₅₀s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4 .

HY-147372

SJ000063181	TGF-beta/Smad	Metabolic Disease
SJ000063181 is a potent BMP signaling activator with an EC₅₀ ≤1 µM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos .

HY-16712

LDN-214117 1 Publications Verification	TGF-β Receptor	Cancer
LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC₅₀ value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC₅₀ value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) ^[2]

HY-RS01539

BMP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BMP4 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BMP4 Human Pre-designed siRNA Set A BMP4 Human Pre-designed siRNA Set A

Recombinant Proteins Recommended:

BMP-4

Species:	Human (4) Mouse (2) Pig (1)
Tag:	His (4) Tag Free (2) Fc (1)
Source:	HEK293 (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P74379

	BMP-4 Protein, Mouse (HEK293, Fc) 1 Publications Verification BMP-2B; BMP-4; Bone morphogenetic protein 4; DVR4	Mouse	HEK293
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. BMP-4 Protein, Mouse (HEK293, Fc) has a total length of 116 amino acids (S293-R408), is expressed in HEK293 cells with N-terminal rFc-tag.

HY-P7007

	BMP-4 Protein, Human 5+ Cited Publications rHuBMP-4; BMP-2B	Human	E. coli
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. BMP-4 Protein, Human has a total length of 116 amino acids (S293-R408), is expressed in E. coli cells with tag free.

HY-P7007A

	BMP-4 Protein, Human (His) rHuBMP-4; BMP-2B	Human	E. coli
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. BMP-4 Protein, Human (His) has a total length of 116 amino acids (S293-R408), is expressed in E. coli cells with N-terminal 6*His-tag.

HY-P700163AF

	*Animal-Free BMP-4* Protein, Mouse (His)** Bone genetic protein 4; BMP4; Bone morphogenetic protein 4; zBMP-4	Mouse	E. coli
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. Animal-Free BMP-4 Protein, Mouse (His) has a total length of 106 amino acids (K303-R408), is expressed in E. coli cells with C-terminal His-tag.

HY-P700230AF

	*Animal-Free BMP-4* Protein, Pig (His)** BMP-2B; BMP-4; Bone morphogenetic protein 4; DVR4	Pig	E. coli
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. Animal-Free BMP-4 Protein, Pig (His) has a total length of 182 amino acids (R43-C224), is expressed in E. coli cells with C-terminal His-tag.

HY-P700027AF

	*Animal-Free BMP-4* Protein, Human (His)** BMP-2B; DVR4	Human	E. coli
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. Animal-Free BMP-4 Protein, Human (His) has a total length of 106 amino acids (K303-R408), is expressed in E. coli cells with a C-terminal His-tag.

HY-P703875

	BMP4 Protein, Human (E399D) bone morphogenetic protein 4	Human	E. coli

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HY-P82540

	BMP4 Antibody (YA2285) BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B	WB, ICC/IF, IP	Human
	BMP4 Antibody (YA2285) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2285), targeting BMP4, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). BMP4 Antibody (YA2285) can be used for WB, ICC/IF, IP experiment in human background.

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BMP4 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
BMP4 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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