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Bioassay

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Endogenous Metabolite (6) GABA Receptor (1) Herbicide (1) HPPD (1) Isotope-Labeled Compounds (1) PD-1/PD-L1 (1) PI3K (1)
By Research Areas:	Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015343

3-Methoxyphenylacetic acid m-Methoxyphenylacetic acid	Endogenous Metabolite	Others
3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot .

HY-W004599

Bicinchoninic acid 5+ Cited Publications	Herbicide	Others
Bicinchoninic acid (compound 8) is an AHAS inhibitor, in an in vivo bioassay targeting the root growth inhibition of rapeseed, at a concentration of 100 μg/mL, it exhibited very low activity, with only a 1.4% root length inhibition rate .

HY-112102

(22S,23S)-Homobrassinolide SSHB	Akt PI3K Endogenous Metabolite	Metabolic Disease
(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active .

HY-B0226S

Nitrofurazone-13C,15N2 Nitrofural-¹³C,¹⁵N₂	Isotope-Labeled Compounds	Infection
Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

HY-N7374

Cyperin	Endogenous Metabolite	Infection
Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola. It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC₅₀=89 μM). Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC₅₀=38.4 μM).

HY-127119

Benanserin hydrochloride	Endogenous Metabolite	Neurological Disease
Benanserin hydrochloride is a serotonin antagonist with psychopharmacological activity. Benanserin hydrochloride can be used to study specific behavioral manifestations in monitoring systems for drug effects. The effects of Benanserin hydrochloride can be sensitively and effectively assessed, for example, by measuring muscle movement capacity and reaction time. Benanserin hydrochloride is suitable for monitoring specific muscle physiological changes. The biological activity of Benanserin hydrochloride can provide reproducible bioassay parameters for experiments .

HY-167688

GSK-1562590	Endogenous Metabolite	Cardiovascular Disease
GSK-1562590 is a uropeptide-II receptor antagonist with high affinity and selectivity. GSK-1562590 exhibits significant antagonistic activity in multiple bioassays and, in contrast, displays relatively sustained receptor binding times. GSK-1562590 can inhibit human urinary peptide-II-induced aortic contraction in rats in experiments, and its effect can last for at least 24 hours .

HY-W015343R

3-Methoxyphenylacetic acid (Standard)	Endogenous Metabolite	Others

HY-161818

LLW-018	PD-1/PD-L1	Inflammation/Immunology
LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC₅₀ value of 2.61 nM. LLW-018 can interrupt PD-1/PD-L1 interaction with an IC₅₀ value of 0.88 μM by cell-based PD-1/PD-L1 blockade bioassays. LLW-018 has the potential for immunotherapy research .

HY-163559

HPPD-IN-4	HPPD	Others
HPPD-IN-4 (Compound III-29) is a selective inhibitor of HPPD with anIC₅₀ of 0.19 μM. HPPD-IN-4 is primarily used in the study of high-efficiency herbicides .

HY-130349

Emamectin B1a L-656,748	GABA Receptor	Infection
Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors α1β1γ2, α1β2γ2, and α1β3γ2 with IC₅₀s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC₅₀=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015343

3-Methoxyphenylacetic acid m-Methoxyphenylacetic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot .

HY-W015343R

3-Methoxyphenylacetic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite

Cat. No.	Product Name	Chemical Structure

HY-B0226S

Nitrofurazone-13C,15N2
Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

Nitrofurazone-13C,15N2

Nitrofurazone- ¹³C, ¹⁵N₂ (Nitrofural- ¹³C, ¹⁵N₂) is the ¹³C and ¹⁵N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .

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