CD34

By Targets:	Apoptosis (6) Aryl Hydrocarbon Receptor (1) Aurora Kinase (1) Bacterial (4) Bcr-Abl (2) c-Myc (1) DNA/RNA Synthesis (1) Fungal (1) HDAC (1) Histone Methyltransferase (1) JAK (1) Kinesin (1) Microtubule/Tubulin (1) Scavenger Receptor Class B type I (SR-BI） (1) Small Interfering RNA (siRNA) (1) STAT (1) Thrombopoietin Receptor (4) Transmembrane Glycoprotein (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Infection (5) Inflammation/Immunology (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990351

*Anti-CD34* Antibody**	Transmembrane Glycoprotein	Inflammation/Immunology
The Anti-CD34 Antibody is a human-derived antibody expressed in CHO, targeting *CD34. The Anti-CD34* Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD34 Antibody can be referenced from Human IgG1 kappa, Isotype Control (HY-P99001).

HY-106784

Ajoene	Fungal Apoptosis	Infection Cancer
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

HY-110208

BRD9876 1 Publications Verification	Kinesin Microtubule/Tubulin	Cancer
BRD9876 is the “rigor” inhibitor that locks kinesin-5 (Eg5) in a state with enhanced microtubules (MTs) binding, leading to bundling and stabilization of MTs. BRD9876 interacts with the tyrosine 104 residue that is part of the α4-α6 allosteric binding pocket. BRD9876 specifically targets microtubule-bound Eg5 and selectively inhibits myeloma over CD34 cells. BRD9876 has the potential for multiple myeloma (MM) research .

HY-150109A

Purinostat	HDAC	Cancer
Purinostat is a selective inhibitor of HDAC I/IIb with anti-leukemic activity. Purinostat mesylate (HY-150109), the mesylate salt of Purinostat, inhibits the survival of Ph+ leukemic cells and CD34+ leukemic cells derived from CML patients. Purinostat mesylate targets HDAC I/IIb to inhibit several important factors for leukemic stem cell (LSC) survival, including c-Myc, β-Catenin, E2f, Ezh2, Alox5, and mTOR. Purinostat mesylate increases glutamate metabolism in LSC by increasing GLS1 .

HY-RS02236

CD34 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD34 Human Pre-designed siRNA Set A contains three designed siRNAs for CD34 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD34 Human Pre-designed siRNA Set A CD34 Human Pre-designed siRNA Set A

HY-P990274

*Anti-Canine CD34* Antibody (1H6)**	Transmembrane Glycoprotein	Others
Anti-Canine CD34 Antibody (1H6) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to canine CD34.

HY-15001A

Stemregenin 1 hydrochloride SR1 hydrochloride	Aryl Hydrocarbon Receptor	Others
Stemregenin 1 hydrochloride is a purine derivative that antagonizes aryl hydrocarbon receptor signaling in CD34+ cells. IC₅₀ The value is 127 nM. Stemregenin 1 hydrochloride can be used to expand the pluripotency of hematopoietic stem cells (HSC) in stem cell studies .

HY-150239

BAY-364 BAY-299N	DNA/RNA Synthesis	Cancer
BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34 ⁺ cells and K562 cells with IC₅₀ values of 1.0 µM, 10.4 µM and 10.0 µM respectively .

HY-125090

PHA-680626	Aurora Kinase c-Myc Bcr-Abl Histone Methyltransferase Apoptosis	Cancer
PHA-680626 is an effective inhibitor of the interaction between Aurora-A and N-Myc. PHA-680626 inhibits kinase activity of AURKA and Bcr-Abl, and induces N-Myc degradation. PHA-680626 decreases phosphorylation of CrkL and histone H3. PHA-680626 shows anti-proliferative and pro-apoptotic activity on Imatinib (HY-15463)-resistant chronic myeloid leukemia cell lines and primary CD34+ cells .

HY-108417

Debio 0617B	STAT JAK Bcr-Abl	Cancer
Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34 ⁺ stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors .

HY-P990352

Anti-CD36 Antibody	Scavenger Receptor Class B type I (SR-BI）	Inflammation/Immunology
Anti-CD36 Antibody is a humanized antibody expressed in CHO that targets CD36. The Anti-CD36 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CD36 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-15306

Eltrombopag Maximum Cited Publications 15 Publications Verification SB-497115	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well .

HY-15306R

Eltrombopag (Standard)	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag (Standard) is the analytical standard of Eltrombopag. This product is intended for research and analytical applications. Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well .

HY-15306AR

Eltrombopag (Olamine) (Standard)	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag (Olamine) (Standard) is the analytical standard of Eltrombopag (Olamine). This product is intended for research and analytical applications. Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well .

HY-15306A

Eltrombopag Olamine Maximum Cited Publications 15 Publications Verification Eltrombopag diethanolamine salt; SB-497115GR	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well .

Cat. No.	Product Name

HY-K0305

*Human CD34⁺ Cells Negative Selection Kit*
MCE Human CD34⁺ Cells Negative Selection Kit is designed for the isolation of CD34⁺ cells from human cord blood mononuclear cells (CBMC) or human peripheral blood mononuclear cells (PBMC).

Cat. No.	Product Name	Target	Research Area

HY-P990351

*Anti-CD34* Antibody**	Transmembrane Glycoprotein	Inflammation/Immunology
The Anti-CD34 Antibody is a human-derived antibody expressed in CHO, targeting *CD34. The Anti-CD34* Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD34 Antibody can be referenced from Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990274

*Anti-Canine CD34* Antibody (1H6)**	Transmembrane Glycoprotein	Others
Anti-Canine CD34 Antibody (1H6) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to canine CD34.

HY-P990352

Anti-CD36 Antibody	Scavenger Receptor Class B type I (SR-BI）	Inflammation/Immunology
Anti-CD36 Antibody is a humanized antibody expressed in CHO that targets CD36. The Anti-CD36 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CD36 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-106784

Ajoene	Infection Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Fungal Apoptosis
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

Recombinant Proteins Recommended:

CD34

Species:	Human (4) Rat (1) Mouse (1)
Tag:	His (3) Fc (3)
Source:	HEK293 (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P72734

	CD34 Protein, Human (HEK293, His) Hematopoietic progenitor cell antigen CD34; CD34	Human	HEK293
	CD34 protein, a potential adhesion molecule, is vital in early hematopoiesis, aiding stem cell attachment to the bone marrow's extracellular matrix or stromal cells. It potentially serves as a scaffold for lineage-specific glycans, facilitating interaction with lectins on stromal cells. CD34 also presents carbohydrate ligands to selectins, enhancing its role in cell adhesion processes. CD34 Protein, Human (HEK293, His) is the recombinant human-derived CD34 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD34 Protein, Human (HEK293, His) is 259 a.a., with molecular weight of 60-90 kDa.

HY-P74304

	CD34 Protein, Rat (HEK293, Fc) Hematopoietic progenitor cell antigen CD34; CD34; HPCA1	Rat	HEK293
	CD34 Protein is a transmembrane phosphoglycoprotein that exists on the surface of human and various animal cells. CD34 Protein is used as a cellular marker for hematopoietic stem cell sorting and as an islet endocrine cell marker. CD34 Protein plays an important role in cell adhesion, inflammatory cell chemotaxis, cell proliferation and differentiation, and enhancement of inflammatory response. CD34 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD34 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77524

	CD34 Protein, Human (Biotinylated, HEK293, His) Hematopoietic progenitor cell antigen CD34; CD34	Human	HEK293
	CD34 protein, a potential adhesion molecule, is vital in early hematopoiesis, aiding stem cell attachment to the bone marrow's extracellular matrix or stromal cells. It potentially serves as a scaffold for lineage-specific glycans, facilitating interaction with lectins on stromal cells. CD34 also presents carbohydrate ligands to selectins, enhancing its role in cell adhesion processes. CD34 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived CD34 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77525

	CD34 Protein, Human (Biotinylated, HEK293, Fc) Hematopoietic progenitor cell antigen CD34; CD34	Human	HEK293
	CD34 protein, a potential adhesion molecule, is vital in early hematopoiesis, aiding stem cell attachment to the bone marrow's extracellular matrix or stromal cells. It potentially serves as a scaffold for lineage-specific glycans, facilitating interaction with lectins on stromal cells. CD34 also presents carbohydrate ligands to selectins, enhancing its role in cell adhesion processes. CD34 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived CD34 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74305

	CD34 Protein, Mouse (HEK293, His) Hematopoietic progenitor cell antigen CD34; CD34; HPCA1	Mouse	HEK293
	CD34 protein functions as a potential adhesion molecule, aiding early hematopoiesis by facilitating stem cell attachment to the bone marrow extracellular matrix or stromal cells. It acts as a scaffold for lineage-specific glycans, enabling stem cells to bind to lectins on stromal cells or other marrow components. Moreover, CD34 may present carbohydrate ligands to selectins, contributing to cell adhesion processes. CD34 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD34 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74306

	CD34 Protein, Human (HEK293, Fc) Hematopoietic progenitor cell antigen CD34; CD34; HPCA1	Human	HEK293
	CD34 protein, a potential adhesion molecule, is vital in early hematopoiesis, aiding stem cell attachment to the bone marrow's extracellular matrix or stromal cells. It potentially serves as a scaffold for lineage-specific glycans, facilitating interaction with lectins on stromal cells. CD34 also presents carbohydrate ligands to selectins, enhancing its role in cell adhesion processes. CD34 Protein, Human (HEK293, Fc) is the recombinant human-derived CD34 protein, expressed by HEK293 , with C-hFc labeled tag.

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HY-P81098

	CD34 Antibody CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN.	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse
	CD34 Antibody is an unconjugated, approximately 39 kDa, rabbit-derived, anti-CD34 polyclonal antibody. CD34 Antibody can be used for: WB, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat, dog, pig, cow, rabbit background without labeling.

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Cat. No.	Product Name		Classification

HY-RS02236

CD34 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CD34 Human Pre-designed siRNA Set A contains three designed siRNAs for CD34 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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