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Results for "

Chemical cross-linking

" in MedChemExpress (MCE) Product Catalog:

26

Inhibitors & Agonists

20

Biochemical Assay Reagents

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107783
    Sulfo-GMBS

    		Others Cancer
    Sulfo-GMBS is a cross-linking agent widely used in chemical modification and coupling reactions of proteins and peptides. Among the amine-sulfhydryl cross-linkers, Sulfo-GMBS generated the largest number of cross-links and covered most of the cross-links that were identified with AMAS and GMBS .
    Sulfo-GMBS
  • HY-W041994
    GMBS

    		Biochemical Assay Reagents Others
    GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins .
    GMBS
  • HY-W341499
    5-Formyl-2'-deoxyuridine

    		Endogenous Metabolite Others
    5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .
    5-Formyl-2'-deoxyuridine
  • HY-48999A
    FSK hydrochloride

    		Others Cancer
    FSK hydrochloride is fluorosulfonyloxybenzoyl-l-lysine, with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride is a modified nanomolecule that targets the epidermal growth factor receptor (EGFR), creating a covalent binding that results in irreversible binding. FSK hydrochloride captures unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues beyond Cys, and cross-linking at the binding periphery. FSK hydrochloride enables the construction of bioreactive SuFEx systems for creating covalent bonds in different proteins in vitro and in vivo .
    FSK hydrochloride
  • HY-W127344
    Oleoyl Chloride

    		Biochemical Assay Reagents Others
    Oleoyl chloride A pungent-smelling liquid commonly used as a reagent in organic synthesis, especially for the production of a variety of organic compounds, including pharmaceuticals and agrochemicals. In addition, it can also be used as a cross-linking agent or surfactant in polymer chemistry. Its unique chemical properties make it an important ingredient in a variety of industrial processes, including petrochemical refining and materials science.
    Oleoyl Chloride
  • HY-W017588
    N-(2-Hydroxyethyl)maleimide

    		Biochemical Assay Reagents Others
    N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis .
    N-(2-Hydroxyethyl)maleimide
  • HY-129655
    Sulfo-SMPB sodium

    		ADC Linker Cancer
    Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
    Sulfo-SMPB sodium
  • HY-W1049071H
    HO-PEG-SCM (MW 2000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 2000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 2000)
  • HY-W1049071C
    HO-PEG-SCM (MW 20000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 20000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 20000)
  • HY-W1049071A
    HO-PEG-SCM (MW 5000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 5000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 5000)
  • HY-W1049071I
    HO-PEG-SCM (MW 3400)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 3400) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 3400)
  • HY-W1049071D
    HO-PEG-SCM (MW 40000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 40000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 40000)
  • HY-W1049071B
    HO-PEG-SCM (MW 10000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 10000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 10000)
  • HY-W1049071E
    HO-PEG-SCM (MW 1000)

    		Biochemical Assay Reagents Others
    HO-PEG-SCM (MW 1000) is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.
    HO-PEG-SCM (MW 1000)
  • HY-W115727A
    Polyacrylamide,Anion,Mw 14-16 million

    PAM,Anion,Mw 14-16 million

    		 Biochemical Assay Reagents Others
    Polyacrylamide, Anion, Mw 14-16 million is a multifunctional high molecular weight anionic polyacrylamide copolymer. The anionic properties of Polyacrylamide, Anion, Mw 14-16 million enable it to be used as a flocculant to achieve charge neutralization and aggregation, while its high molecular weight properties provide viscoelastic properties for fluid applications. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, achieve controlled release as a drug carrier, respond to temperature/pH stimulation as a smart material, and can also be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical embedding, covalent bonding or chemical cross-linking. Polyacrylamide can be used in biomedical engineering, environmental management and industrial applications .
    Polyacrylamide,Anion,Mw 14-16 million
  • HY-145149
    Duostatin 5

    		ADC Cytotoxin Cancer
    Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
    Duostatin 5
  • HY-W142308
    Diammonium dithiodiglycolate

    		Biochemical Assay Reagents
    Diammonium dithiodiglycolate is a film-forming polymer used as a crosslinking agent, with the activity of promoting crosslinking of materials and enhancing their stability. Diammonium dithiodiglycolate plays a key role in biomedical applications, especially in the preparation of biocompatible materials. The unique chemical properties of Diammonium dithiodiglycolate make it an ideal choice to achieve high-performance polymer properties.
    Diammonium dithiodiglycolate
  • HY-W1048572C
    N3-PEG-NH2 (MW 1000)

    Azide-PEG-Amine (MW 1000)

    		 Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 1000) (Azide-PEG-Amine (MW 1000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 1000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 1000)
  • HY-W1048572H
    N3-PEG-NH2 (MW 10000)

    Azide-PEG-Amine (MW 10000)

    		 Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 10000) (Azide-PEG-Amine (MW 10000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 10000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 10000)
  • HY-W1048572E
    N3-PEG-NH2 (MW 5000)

    		Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 5000) (Azide-PEG-Amine (MW 5000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 5000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 5000)
  • HY-W1048572I
    N3-PEG-NH2 (MW 20000)

    Azide-PEG-Amine (MW 20000)

    		 Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 20000) (Azide-PEG-Amine (MW 20000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 20000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 20000)
  • HY-W1048572A
    N3-PEG-NH2 (MW 2000)

    		Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 2000) (Azide-PEG-Amine (MW 2000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 2000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 2000)
  • HY-W1048572D
    N3-PEG-NH2 (MW 3400)

    Azide-PEG-Amine (MW 3400)

    		 Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 3400) (Azide-PEG-Amine (MW 3400)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 3400) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 3400)
  • HY-W1048572J
    N3-PEG-NH2 (MW 40000)

    Azide-PEG-Amine (MW 40000)

    		 Biochemical Assay Reagents Others
    N3-PEG-NH2 (MW 40000) (Azide-PEG-Amine (MW 40000)) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG-NH2 (MW 40000) is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
    N3-PEG-NH2 (MW 40000)
  • HY-W250309
    Pentaerythritol tetra(3-mercaptopropionate)

    		Biochemical Assay Reagents Others
    Pentaerythritol tetra(3-mercaptopropionate)It is a class of organic compounds containing both pentaerythritol and mercaptopropionate groups. It is commonly used as a stabilizer and crosslinking agent in various chemical and industrial applications. Pentaerythritol tetra(3-mercaptopropionate)Has a variety of properties that make it suitable for these applications, including the ability to increase the mechanical strength, thermal stability and weatherability of polymers and coatings. Additionally, it can be used as a feedstock for the production of other specialty chemicals and materials.
    Pentaerythritol tetra(3-mercaptopropionate)
  • HY-Y0623
    N-Hydroxysuccinimide

    HOSu; 1-Hydroxy-2,5-pyrrolidinedione

    		 Biochemical Assay Reagents Others
    N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .
    N-Hydroxysuccinimide

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