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Cholesterol (Standard)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (7) Antibiotic (3) AP-1 (1) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (7) ATP Citrate Lyase (1) Autophagy (5) Bacterial (4) Biochemical Assay Reagents (2) Caspase (1) Drug Derivative (1) Drug Metabolite (2) Endogenous Metabolite (31) Estrogen Receptor/ERR (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (2) Fungal (1) FXR (1) G protein-coupled Bile Acid Receptor 1 (1) Glutathione Peroxidase (1) Hedgehog (1) HMG-CoA Reductase (HMGCR) (3) Interleukin Related (2) JAK (1) Keap1-Nrf2 (2) Lactate Dehydrogenase (1) LDLR (1) Liposome (3) LXR (2) MicroRNA (1) Mitophagy (1) MMP (1) NF-κB (1) NOD-like Receptor (NLR) (1) p38 MAPK (1) Parasite (1) PARP (1) Phosphodiesterase (PDE) (1) Potassium Channel (1) PPAR (1) Reactive Oxygen Species (ROS) (6) Reference Standards (47) SOD (1) Virus Protease (1) β-catenin (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (16) Infection (5) Inflammation/Immunology (12) Metabolic Disease (28) Neurological Disease (5)

By Targets:

Acyltransferase (7)

Antibiotic (3)

AP-1 (1)

Apical Sodium-Dependent Bile Acid Transporter (1)

Apoptosis (7)

ATP Citrate Lyase (1)

Autophagy (5)

Bacterial (4)

Biochemical Assay Reagents (2)

Caspase (1)

Drug Derivative (1)

Drug Metabolite (2)

Endogenous Metabolite (31)

Estrogen Receptor/ERR (1)

Fatty Acid Synthase (FASN) (2)

Ferroptosis (2)

Fungal (1)

FXR (1)

G protein-coupled Bile Acid Receptor 1 (1)

Glutathione Peroxidase (1)

Hedgehog (1)

HMG-CoA Reductase (HMGCR) (3)

Interleukin Related (2)

JAK (1)

Keap1-Nrf2 (2)

Lactate Dehydrogenase (1)

LDLR (1)

Liposome (3)

LXR (2)

MicroRNA (1)

Mitophagy (1)

MMP (1)

NF-κB (1)

NOD-like Receptor (NLR) (1)

p38 MAPK (1)

Parasite (1)

PARP (1)

Phosphodiesterase (PDE) (1)

Potassium Channel (1)

PPAR (1)

Reactive Oxygen Species (ROS) (6)

Reference Standards (47)

SOD (1)

Virus Protease (1)

β-catenin (1)

By Research Areas:

Cancer (18)

Cardiovascular Disease (16)

Infection (5)

Inflammation/Immunology (12)

Metabolic Disease (28)

Neurological Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Targets Recommended: Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0322R

Cholesterol (Standard) Maximum Cited Publications 37 Publications Verification	Liposome Reference Standards Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Metabolic Disease Cancer
Cholesterol (Standard) is the analytical standard of Cholesterol. This product is intended for research and analytical applications. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0504R

Lovastatin (Standard) 20+ Cited Publications Mevinolin (Standard)	Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Lovastatin (Standard) is the analytical standard of Lovastatin. This product is intended for research and analytical applications. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

HY-W127349R

Cholesterol n-Octanoate (Standard)	Liposome Reference Standards	Others
Cholesterol n-Octanoate (Standard) is the analytical standard of Cholesterol n-Octanoate. This product is intended for research and analytical applications. Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.

HY-N0322BR

Cholesterol (Excipient) (Standard)	Reference Standards Liposome Endogenous Metabolite	Others
Cholesterol (Excipient) (Standard) is the analytical standard of Cholesterol (Excipient) (HY-N0322B). This product is intended for research and analytical applications. Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases. Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by β-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor α (ERRα) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of β-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimer's disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].

HY-107823R

Cholesteryl acetate (Standard)	Endogenous Metabolite	Others
Cholesteryl acetate (Standard) is the analytical standard of Cholesteryl acetate. This product is intended for research and analytical applications. Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .

HY-138694R

5-Benzyloxygramine (Standard)	Antibiotic Reference Standards	Infection
Cholesterol (Excipient) (Standard) is the analytical standard of Cholesterol (Excipient). This product is intended for research and analytical applications. Cholesterol Excipient is a component of cell membranes, and precursors certain hormones, vitamin D and bile acids. Cholesterol Excipient can be used as an excipient in pharmaceutical preparations for its amphiphilicity, good biocompatibility and biodegradability .

HY-N1459R

Campesterol (Standard) (24R)-5-Ergosten-3β-ol (Standard)	Reference Standards Endogenous Metabolite	Cancer
Campesterol (Standard) is the analytical standard of Campesterol. This product is intended for research and analytical applications. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-135221R

Cefcapene pivoxil hydrochloride (Standard)	Reference Standards Bacterial Antibiotic	Infection
Chenodeoxycholic Acid (Standard) is the analytical standard of Chenodeoxycholic Acid. This product is intended for research and analytical applications. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

HY-76847R

Chenodeoxycholic Acid (Standard) CDCA (Standard)	Reference Standards FXR Endogenous Metabolite Autophagy	Metabolic Disease Cancer
Chenodeoxycholic Acid (Standard) is the analytical standard of Chenodeoxycholic Acid. This product is intended for research and analytical applications. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

HY-101722R

Melinamide (Standard) AC 223 (Standard); DL-N-(α-Methylbenzyl)linoleamide (Standard)	Acyltransferase Reference Standards	Metabolic Disease
Melinamide (Standard) is the analytical standard of Melinamide. This product is intended for research and analytical applications. Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM.

HY-113279R

7-Dehydrocholesterol (Standard)	Endogenous Metabolite Reference Standards	Others
7-Dehydrocholesterol (Standard) is the analytical standard of 7-Dehydrocholesterol. This product is intended for research and analytical applications.7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

HY-W020033R

Lanosterol (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease
Lanosterol (Standard) is the analytical standard of Lanosterol. This product is intended for research and analytical applications. Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases[1][2].

HY-B0388R

Probucol (Standard) 1 Publications Verification DH-581 (Standard)	Reference Standards Virus Protease	Metabolic Disease
Probucol (Standard) is the analytical standard of Probucol. This product is intended for research and analytical applications. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.

HY-133962

Cholesteryl erucate	Biochemical Assay Reagents	Others
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

HY-113342R

7-Ketocholesterol (Standard)	Endogenous Metabolite p38 MAPK	Cardiovascular Disease Metabolic Disease
7-Ketocholesterol (Standard) is the analytical standard of 7-Ketocholesterol. This product is intended for research and analytical applications. 7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis (apoptosis) .

HY-101397R

Allopurinol riboside (Standard)	Reference Standards Parasite Drug Metabolite Endogenous Metabolite	Infection
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0686R

Pseudoprotodioscin (Standard)	Reference Standards Fatty Acid Synthase (FASN) MicroRNA	Metabolic Disease
Pseudoprotodioscin (Standard) is the analytical standard of Pseudoprotodioscin. This product is intended for research and analytical applications. Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides .

HY-N1214R

Squalene (Standard) Super Squalene (Standard); trans-Squalene (Standard); AddaVax (Standard)	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Fungal	Infection Cardiovascular Disease
Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-N0324R

Cholic acid (Standard) 10+ Cited Publications	Reference Standards Endogenous Metabolite	Metabolic Disease
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-113224R

Desmosterol (Standard)	Reference Standards Endogenous Metabolite LXR Fatty Acid Synthase (FASN) Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR)	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Desmosterol (Standard) is the analytical standard of Desmosterol. This product is intended for research and analytical applications. Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].

HY-N0131R

Stigmasterol (Standard) Stigmasterin (Standard)	Reference Standards MMP Endogenous Metabolite	Inflammation/Immunology
Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

HY-W089835R

Sodium taurodeoxycholate hydrate (Standard)	Reference Standards G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite	Metabolic Disease
Sodium taurodeoxycholate hydrate (Standard) is the analytical standard of Sodium taurodeoxycholate hydrate. This product is intended for research and analytical applications. Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Sodium taurodeoxycholate hydrate activates the S1PR2 pathway in addition to the TGR5 pathway .

HY-107830R

Methyl cholate (Standard)	Reference Standards Drug Metabolite Others	Metabolic Disease
Methyl cholate (Standard) is the analytical standard of Methyl cholate. This product is intended for research and analytical applications. Methyl Cholate is methyl ester form of Cholic acid. Cholic acid is one of the major bile acids produced by the liver, where it is synthesized from cholesterol[1].

HY-N0324AR

Cholic acid sodium (Standard) Sodium cholate (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Cholic acid (sodium) (Standard) is the analytical standard of Cholic acid (sodium). This product is intended for research and analytical applications. Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2].

HY-113086

CE(16:1(9Z)) 16:1(9Z) CE; 16:1(9Z) Cholesterol ester; Cholesterol Palmitoleate	Endogenous Metabolite	Cardiovascular Disease
Cholesteryl palmitoleate is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE-/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.

HY-109567R

Gemcabene (Standard)	Others	Metabolic Disease Inflammation/Immunology
Gemcabene (Standard) is the analytical standard of Gemcabene. This product is intended for research and analytical applications. Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity .

HY-100400AR

K-604 dihydrochloride (Standard)	Reference Standards Acyltransferase	Cardiovascular Disease
K-604 (dihydrochloride) (Standard) is the analytical standard of K-604 (dihydrochloride). This product is intended for research and analytical applications. K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μM.

HY-121776R

Nicomol (Standard)	Drug Derivative	Cardiovascular Disease
Nicomol (Standard) is the analytical standard of Nicomol. This product is intended for research and analytical applications. Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids .

HY-17376R

Ezetimibe (Standard) 5+ Cited Publications SCH 58235 (Standard)	Reference Standards Keap1-Nrf2 Autophagy	Cardiovascular Disease Cancer
Ezetimibe (Standard) is the analytical standard of Ezetimibe. This product is intended for research and analytical applications. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

HY-N2419R

Erythrodiol (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Erythrodiol (Standard) is the analytical standard of Erythrodiol. This product is intended for research and analytical applications. Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis .

HY-N8425R

Octacosanoic acid (Standard) Montanic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Octacosanoic acid (Standard) is the analytical standard of Octacosanoic acid. This product is intended for research and analytical applications. Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-B1209R

Etofylline (Standard) 7-(β-Hydroxyethyl)theophylline (Standard)	Phosphodiesterase (PDE) Reference Standards	Cardiovascular Disease
Etofylline (Standard) is the analytical standard of Etofylline. This product is intended for research and analytical applications. Etofylline (7-(β-Hydroxyethyl)theophylline) is a N-7-substituted derivative of Theophylline. Etofylline is a bronchodilator which can be used for the research of asthma. Etofylline is also an anticholesteremic and reduces total cholesterol level in the blood .

HY-113486R

Lathosterol (Standard)	Endogenous Metabolite Reference Standards SOD Lactate Dehydrogenase	Metabolic Disease
Lathosterol (Standard) is the analytical standard of Lathosterol (HY-113486). This product is intended for research and analytical applications. Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{[1] .}

HY-129459R

α-Tocotrienol (Standard)	Reference Standards Endogenous Metabolite	Cardiovascular Disease Neurological Disease
α-Tocotrienol (Standard) is the analytical standard of α-Tocotrienol. This product is intended for research and analytical applications. α-Tocotrienol is an isoform of vitamin E and found in vegetables, fruits, seeds, nuts, grains, and oils. Vitamin E plays a role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.

HY-129123R

ML318 (Standard)	Reference Standards Antibiotic	Infection
7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .

HY-W018512R

7-Ketolithocholic acid (Standard) 3α-Hydroxy-7-oxo-5β-cholanic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .

HY-113134R

25-Hydroxycholesterol (Standard)	Endogenous Metabolite	Inflammation/Immunology
25-Hydroxycholesterol (Standard) is the analytical standard of 25-Hydroxycholesterol. This product is intended for research and analytical applications. 25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.

HY-100399AR

Nevanimibe hydrochloride (Standard) PD-132301 hydrochloride (Standard); ATR101 hydrochloride (Standard)	Reference Standards Acyltransferase Apoptosis	Cancer
Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .

HY-W012946R

2-Furoic acid (Standard) Pyromucic acid (Standard)	Reference Standards ATP Citrate Lyase Acyltransferase Endogenous Metabolite	Metabolic Disease
2-Furoic acid (Standard) is the analytical standard of 2-Furoic acid. This product is intended for research and analytical applications. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-122778R

δ-Tocotrienol (Standard)	Reference Standards NF-κB AP-1 Caspase Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
δ-Tocotrienol (Standard) is the analytical standard of δ-Tocotrienol. This product is intended for research and analytical applications. δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.

HY-131389

Cholesteryl heptadecanoate	Biochemical Assay Reagents	Others
Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .

HY-B0144R

Pitavastatin Calcium (Standard) NK-104 hemicalcium (Standard); Pitavastatin hemicalcium (Standard)	Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin (Calcium) (Standard) is the analytical standard of Pitavastatin (Calcium). This product is intended for research and analytical applications. Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC₅₀ of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .

HY-13215R

Avasimibe (Standard)	Acyltransferase	Cancer
Avasimibe (Standard) is the analytical standard of Avasimibe. This product is intended for research and analytical applications. Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer .

HY-A0152R

D-Thyroxine (Standard) D-T4 (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
D-Thyroxine (Standard) is the analytical standard of D-Thyroxine (HY-A0152). This product is intended for research and analytical applications. D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .

HY-113341R

7β-Hydroxycholesterol (Standard)	Reactive Oxygen Species (ROS) Apoptosis Interleukin Related	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
7β-Hydroxycholesterol (Standard) is the analytical standard of 7β-Hydroxycholesterol. This product is intended for research and analytical applications. 7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol can induce cellular oxidative stress, apoptosis, and necrosis, resulting in cytotoxicity. 7β-hydroxycholesterol has antitumor activity .

HY-128749AR

D-Glucaric acid tetrahydrate (Standard) Calcium D-glucarate tetrahydrate (Standard)	Endogenous Metabolite Reference Standards Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
D-Glucaric acid tetrahydrate (Standard) (Calcium D-glucarate tetrahydrate (Standard)) is the analytical standard of D-Glucaric acid tetrahydrate (HY-128749A). This product is intended for research and analytical applications. D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is present in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can inhibit tumor cell proliferation and inflammation, and induce apoptosis .

HY-N4103R

Fucosterol (Standard)	Reference Standards PARP Endogenous Metabolite	Metabolic Disease Cancer
Fucosterol (Standard) is the analytical standard of Fucosterol. This product is intended for research and analytical applications. Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .

HY-N0246R

Saikosaponin A (Standard)	Reference Standards LXR Bacterial	Metabolic Disease Inflammation/Immunology
Saikosaponin A (Standard) is the analytical standard of Saikosaponin A. This product is intended for research and analytical applications. Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also act as a potential peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis .

HY-42680R

D-Tagatose (Standard) D-(-)-Tagatose (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
D-Tagatose (Standard) is the analytical standard of D-Tagatose. This product is intended for research and analytical applications. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice, and beverages. D-Tagatose is also a potential antidiabetic agent for the research of type II diabetes and a prebiotic to help elevate beneficial bacteria in the colon, prevent colon cancer, and lower cholesterol .

HY-N0527R

Pentagalloylglucose (Standard) Penta-O-galloyl-β-D-glucose (Standard); 1,2,3,4,6-Pentagalloyl glucose (Standard)	Reference Standards JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology Cancer
Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .

Cat. No.	Product Name	Type

HY-W127349R

Cholesterol n-Octanoate (Standard)

Drug Delivery

Cholesterol n-Octanoate (Standard) is the analytical standard of Cholesterol n-Octanoate. This product is intended for research and analytical applications. Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.

HY-133962

Cholesteryl erucate	Drug Delivery
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

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