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Results for "

Coclaurine

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

5

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N3610
    Coclaurine
    1 Publications Verification

    		 nAChR Neurological Disease
    Coclaurine is a class of tetrahydroisoquinoline alkaloids that can be isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist .
    Coclaurine
  • HY-N2550A
    (+)-Coclaurine hydrochloride

    (+)-(R)-Coclaurine hydrochloride; (R)-Coclaurine hydrochloride; d-Coclaurine hydrochloride

    		 Others Neurological Disease
    (+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity .
    (+)-Coclaurine hydrochloride
  • HY-N2037
    Higenamine
    3 Publications Verification

    NorCoclaurine; Demethyl-Coclaurine

    		 MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis Cardiovascular Disease Endocrinology
    Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
    Higenamine
  • HY-W705106
    (-)-Coclaurine hydrochloride

    (-)-(S)-Coclaurine hydrochloride; (S)-Coclaurine hydrochloride; l-Coclaurine hydrochloride

    		 nAChR Neurological Disease
    (-)-Coclaurine hydrochloride (compound I) is a class of tetrahydroisoquinoline alkaloids that can be isolated from Sarcopetalum harveyanum. (-)-Coclaurine hydrochloride is a nicotinic acetylcholine receptor (nAChRs) antagonist .
    (-)-Coclaurine hydrochloride
  • HY-N2550
    (+)-Coclaurine

    (+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine

    		 Others Neurological Disease
    (+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity .
    (+)-Coclaurine
  • HY-N11099
    (±)-Coclaurine

    		Others Cardiovascular Disease
    (±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects .
    (±)-Coclaurine
  • HY-N2037AS
    Higenamine-d4 hydrochloride

    NorCoclaurine-d4 hydrochloride; Demethyl-Coclaurine-d4 hydrochloride

    		 ROS Kinase MDM-2/p53 Apoptosis Isotope-Labeled Compounds Cancer
    Higenamine-d4 (Norcoclaurine-d4; Demethyl-Coclaurine-d4) hydrochloride is deuterium-labeled Higenamine (hydrochloride) (HY-N2037A) .
    Higenamine-d4 hydrochloride

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