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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

Complement C3 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Complement System (2)
By Research Areas:	Inflammation/Immunology (3)

2

Inhibitors & Agonists

3

Inhibitory Antibodies

4

Antibodies

Targets Recommended: Complement System ADC Antibody Antibody-Drug Conjugates (ADCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

Riliprubart SAR 445088	Complement System	Inflammation/Immunology
Riliprubart (SAR445088) is an *anti-C1s* humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a .

Cat. No.	Product Name	Target	Research Area

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

Riliprubart SAR 445088	Complement System	Inflammation/Immunology
Riliprubart (SAR445088) is an *anti-C1s* humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a .

NGM-621	Inhibitory Antibodies	Inflammation/Immunology

Cat. No.	Compare	Product Name	Application	Reactivity

	CD35 Antibody (YA1328) C3BR,Complement receptor type 1,C3b/C4b receptor,CD35	IHC-P	Human
	CD35 Antibody (YA1328) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1328), targeting CD35. CD35 Antibody (YA1328) can be used for IHC-P experiment in human background.

	C3 Antibody AHUS5; ARMD9; ASP; Complement C3; Complement factor 3; CPAMD1; HEL S 62p	WB, IHC-P	Human
	C3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 187 kDa, targeting to C3. It can be used for WB,IHC-P assays with tag free, in the background of Human.

	Phospho-CD18 (Ser745) Antibody ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18	WB, IP	Human, Mouse, Rat
	Phospho-CD18 (Ser745) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 85 kDa, targeting to Phospho-CD18 (Ser745). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

	Complement factor B Antibody (YA2984) C3/C5 convertase; Complement factor B; PBF2; Properdin factor B	WB	Human
	Complement factor B Antibody (YA2984) is a biotin-conjugated non-conjugated IgG antibody, targeting Complement factor B, with a predicted molecular weight of 86 kDa (observed band size: 100 kDa). Complement factor B Antibody (YA2984) can be used for WB experiment in human background.

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