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D-Xylulose

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

1

Recombinant Proteins

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W010256
    D-Xylulose

    		Endogenous Metabolite Metabolic Disease
    D-xylulose is a precursor of the pentiol D-arabitol.
    D-Xylulose
  • HY-E70308
    Glucose isomerase

    		Endogenous Metabolite Others
    Glucose isomerase is a glucose isomerase that catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. Glucose isomerase is thermally stable and can be used to produce fructose syrup at high temperatures above 90°C. Glucose isomerase is widely distributed in prokaryotes .
    Glucose isomerase
  • HY-W010256S
    D-Xylulose-1-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Xylulose-1- 13C is the 13C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi[1][2].
    D-Xylulose-1-13C
  • HY-W010256S1
    D-Xylulose-2-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Xylulose-2- 13C is the 13C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi[1][2].
    D-Xylulose-2-13C
  • HY-161406
    DXPS-IN-1

    		Bacterial Infection
    DXPS-IN-1 (Compound 8) is an inhibitor of 1-deoxy-D-xylulose-5-phosphate synthase (DXPS) with a Ki value of 2.9 nM against EcDXPS. DXPS-IN-1 exhibits antibacterial activity .
    DXPS-IN-1
  • HY-162898
    Antibacterial agent 242

    		Bacterial Infection
    Antibacterial agent 242 is a potent 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) inhibitor against Toxoplasma gondii with an IC50 value of 5.46 μM. Antibacterial agent 242 inhibits the activity of TgDXR enzyme and the proliferation of T. gondii in vitro .
    Antibacterial agent 242
  • HY-W795264
    FR900098

    		Parasite Infection
    FR900098 is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 has no effect on bone marrow red blood cells in NMRI mice .
    FR900098
  • HY-149882
    Antimalarial agent 27

    		Parasite Infection
    Antimalarial agent 27 (compound 11a) is an antimalarial agent, potently targeting to P.falciparum (IC50=0.37 μM). Antimalarial agent 27 acts function via P.falciparum DXR (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibition (IC50=0.11 μM) .
    Antimalarial agent 27
  • HY-122817
    FR900098 sodium

    		Antibiotic Parasite Infection
    FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice .
    FR900098 sodium
  • HY-157840
    Anti-infective agent 9

    		Parasite Infection
    Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC50=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS) .
    Anti-infective agent 9
  • HY-134914
    Fosmidomycin

    		Antibiotic Parasite Infection
    Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
    Fosmidomycin

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