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Pathways Recommended: Cell Cycle/DNA Damage
Results for "

DNA GyrB

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141442
    Dihydronovobiocin

    		Bacterial Antibiotic Infection
    Dihydronovobiocin is a bacterial inhibitor and ATPase inhibitor that can bind to GyrB. Dihydronovobiocin can be used to study the interaction between coumarin antibiotics (such as Novobiocin, Chlorobiocin, and Coumermycin) and DNA gyrase. Dihydronovobiocin also has the potential to study bacterial infections .
    Dihydronovobiocin
  • HY-149925
    DNA Gyrase-IN-6

    		Bacterial DNA/RNA Synthesis Topoisomerase Infection
    Antibacterial agent 138 is a benzothiazole inhibitor of bacterial DNA gyrase and topoisomerase IV. Antibacterial agent 138 exhibits favorable solubility and plasma protein binding. Antibacterial agent 138 has antibacterial activity against Gram-positive and Gram-negative strains. Antibacterial agent 138 is a dual GyrB and ParE inhibitor .
    DNA Gyrase-IN-6
  • HY-147945
    DNA gyrase B-IN-1

    		DNA/RNA Synthesis Bacterial Infection
    DNA gyrase B-IN-1 (compound 13) is a potent DNA gyrase B inhibitor. DNA gyrase B-IN-1 shows inhibition of P. aeruginosa DNA gyrase B, with an IC50 of 2.2 μM. DNA gyrase B-IN-1 has good binding affinity and stability .
    DNA gyrase B-IN-1

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