Ferrous

By Targets:	Autophagy (1) Biochemical Assay Reagents (4) Drug Isomer (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (4) Fluorescent Dye (1) Glutathione Peroxidase (1) NO Synthase (1) PROTACs (1) Reactive Oxygen Species (1) Transferrin Receptor (3)
By Research Areas:	Cancer (6) Cardiovascular Disease (3) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130078

Ferrous bisglycinate	Transferrin Receptor	Metabolic Disease Inflammation/Immunology
Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia .

HY-Y1103

Iron(II) sulfate heptahydrate, 99% Ferrous sulfate heptahydrate, 99%	Biochemical Assay Reagents	Cardiovascular Disease Cancer
Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-B1651

Iron(II) fumarate Ferrous fumarate	Transferrin Receptor	Metabolic Disease Cancer
Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia .

HY-Y1103A

Iron(II) sulfate heptahydrate, for cell culture, 99% Ferrous sulfate heptahydrate, for cell culture, 99%	Biochemical Assay Reagents	Others
Iron(II) sulfate heptahydrate, for cell culture, 99% is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-D2295

Mito-FerroGreen 1 Publications Verification	Fluorescent Dye	Others
Mito-FerroGreen is a mitochondria-specific ferrous ion detection probe with an excitation wavelength of 488nm .

HY-129457

FINO2 5 Publications Verification	Ferroptosis	Cancer
FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation .

HY-B1651R

Iron(II) fumarate (Standard) Ferrous fumarate (Standard)	Transferrin Receptor	Metabolic Disease Cancer
Iron(II) fumarate (Standard) is the analytical standard of Iron(II) fumarate. This product is intended for research and analytical applications. Iron(II) fumarate (Ferrous fumarate) is the iron(II) salt of fumaric acid. Iron(II) fumarate is an orally active dietary supplement and has the potential for iron deficiency anemia treatment .

HY-157367

Bismuth Sulfite Agar Medium	Biochemical Assay Reagents	Others
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .

HY-162310

Anticancer agent 193	Ferroptosis Reactive Oxygen Species Autophagy	Cancer
Anticancer agent 193 (compound D3-3) is an inducer of ferritinophagy, eventually triggering ferroptosis. Anticancer agent 193 induces the production of lipid ROS, and significantly promoted colorectal cancer cells to release the ferrous ion in an autophagy-dependent manner .

HY-157359

Bacterial Organophosphorus Medium	Biochemical Assay Reagents	Others
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .

HY-170509

Ferroptosis-IN-17	Ferroptosis Glutathione Peroxidase	Cardiovascular Disease Neurological Disease Cancer
Ferroptosis-IN-17 (Compound 18) is a ferroptosis (Ferroptosis) inhibitor with an EC₅₀ value of 0.57 μM. Ferroptosis-IN-17 reduces intracellular ferrous ion accumulation, lipid peroxidation, and effectively restores the levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). Ferroptosis-IN-17 shows good solubility and significant metabolic stability in rat plasma. Ferroptosis-IN-17 is promising for research in tumor suppression, neurodegenerative diseases, and cardiovascular diseases .

HY-111914A

Ferroheme	NO Synthase Fatty Acid Synthase (FASN)	Cardiovascular Disease
Ferroheme is the ferrous form of heme in hemoglobin, reversibly binding oxygen as an oxygen carrier. Its free form induces oxidative stress and ferroptosis by releasing iron ions, which catalyze reactive oxygen species generation via Fenton reactions, leading to lipid peroxidation and cell death. This mechanism is critical in pathological contexts like intracerebral hemorrhage and neurodegenerative diseases, making it a target for studying iron-overload disorders and ferroptosis-related pathologies[1][2][3].

HY-163897

PROTAC NCOA4 degrader-1	PROTACs Ferroptosis	Inflammation/Immunology
PROTAC NCOA4 degrader-1 (Compound V3) is a PROTAC NCOA4 degrader (DC₅₀: 3 nM in HeLa cells). PROTAC NCOA4 degrader-1 is a ferroptosis inhibitor. PROTAC NCOA4 degrader-1 reduces NCOA4 levels and downregulates intracellular ferrous iron (Fe ²⁺) levels. PROTAC NCOA4 degrader-1 ameliorates liver damage in a CCl₄-induced acute liver injury model. (Red: NCOA4 ligand (HY-149457). Black: linker (HY-163903). Blue: VHL ligand (HY-138678B)) .

HY-W015600

2-Acetamidophenol Orthocetamol	Drug Isomer	Inflammation/Immunology
2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC₅₀s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe ²⁺), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .

Cat. No.	Product Name	Type

HY-D2295

Mito-FerroGreen 1 Publications Verification	Fluorescent Dyes/Probes
Mito-FerroGreen is a mitochondria-specific ferrous ion detection probe with an excitation wavelength of 488nm .

Cat. No.	Product Name	Type

HY-Y1103

Iron(II) sulfate heptahydrate, 99% Ferrous sulfate heptahydrate, 99%	Buffer Reagents
Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

Iron(II) sulfate heptahydrate, 99%

Ferrous sulfate heptahydrate, 99%

Buffer Reagents

Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-Y1103A

Iron(II) sulfate heptahydrate, for cell culture, 99% Ferrous sulfate heptahydrate, for cell culture, 99%	Buffer Reagents
Iron(II) sulfate heptahydrate, for cell culture, 99% is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-157367

Bismuth Sulfite Agar Medium	Microbial Culture
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .

HY-157359

Bacterial Organophosphorus Medium	Microbial Culture
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .

Cat. No.	Product Name

HY-K0322

*Cell Ferrous* Iron (Fe²⁺) Assay Kit (Fluorometric)**
MCE Cell Ferrous Iron (Fe²⁺) Assay Kit (Fluorometric) utilizes fluorescence detection technology to analyze the levels of ferrous ions (Fe²⁺) in cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-111914A

Ferroheme	Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	NO Synthase Fatty Acid Synthase (FASN)
Ferroheme is the ferrous form of heme in hemoglobin, reversibly binding oxygen as an oxygen carrier. Its free form induces oxidative stress and ferroptosis by releasing iron ions, which catalyze reactive oxygen species generation via Fenton reactions, leading to lipid peroxidation and cell death. This mechanism is critical in pathological contexts like intracerebral hemorrhage and neurodegenerative diseases, making it a target for studying iron-overload disorders and ferroptosis-related pathologies[1][2][3].

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

MCE Kits

Natural
Products