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Iron(II) fumarate  (Synonyms: Ferrous fumarate)

Cat. No.: HY-B1651 Purity: ≥95.0%
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Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia.

For research use only. We do not sell to patients.

Iron(II) fumarate Chemical Structure

Iron(II) fumarate Chemical Structure

CAS No. : 141-01-5

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Iron(II) fumarate Related Antibodies

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Description

Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia[1][4].
In Vitro

Iron(II) fumarate (0.32%, 0.64%; 24 h) can restore the metabolic pathway disruption caused by cypermethrin, enhance the tolerance and cell viability of BmN cells to cypermethrin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Iron(II) fumarate Related Antibodies

Cell Viability Assay[1].

Cell Line: BmN cells
Concentration: 0.32%, 0.64%
Incubation Time: 24 h
Result: Enhanced cell tolerance to cypermethrin and increased cell viability.
In Vivo

Iron(II) fumarate (0.32%, 0.64%; p.o.) can alleviate the damage of cypermethrin to silkworms[1].
Iron(II) fumarate (200-2000 mg/kg; 4 weeks; p.o.) can induce oxidative stress in the liver and colon of rats[2].
Iron(II) fumarate (3% of body weight; 100 mg ferrous fumarate (F) per kilogram feed (g/kg); twice daily; 6 weeks; p.o.) can alter the intestinal morphology and microbiota of Yellow River carp, increasing the diversity and richness of the microbiota[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: p50 and 8y silkworm strains[1].
Dosage: 0.32%, 0.64%
Administration: Oral gavage (p.o.)
Result: Improved the resistance of silkworms to cypermethrin.
Animal Model: Male albino rats (clinical average weight = 65 g)[2].
Dosage: 200-2000 mg/kg
Administration: Oral gavage (p.o.); 4 weeks
Result: Increased iron content and TBA-RS levels in the liver.
Animal Model: Yellow River Carp[3].
Dosage: 3% of body weight; 100 mg ferrous fumarate (F) per kilogram feed (g/kg)
Administration: Oral gavage (p.o.); twice daily; 6 weeks
Result: Promoted the development of intestinal villi and increased the thickness of the intestinal muscle layer.
Clinical Trial
Molecular Weight

169.90

Formula

C4H2FeO4
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C([O-])/C=C/C([O-])=O.[Fe+2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

RT, stored under nitrogen
Solvent & Solubility
In Vitro: 

1M HCl : 5 mg/mL (29.43 mM; ultrasonic and warming and heat to 60°C)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8858 mL 29.4291 mL 58.8582 mL
5 mM 1.1772 mL 5.8858 mL 11.7716 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥95.0%

COA (248 KB) IR (136 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
1M HCl 1 mM 5.8858 mL 29.4291 mL 58.8582 mL 147.1454 mL
5 mM 1.1772 mL 5.8858 mL 11.7716 mL 29.4291 mL
10 mM 0.5886 mL 2.9429 mL 5.8858 mL 14.7145 mL
15 mM 0.3924 mL 1.9619 mL 3.9239 mL 9.8097 mL
20 mM 0.2943 mL 1.4715 mL 2.9429 mL 7.3573 mL
25 mM 0.2354 mL 1.1772 mL 2.3543 mL 5.8858 mL
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Iron(II) fumarate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Iron(II)141-01-5FerrousOthersAntianemicorallyfumaricdietarysupplementInhibitorinhibitorinhibit

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