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Firefly luciferase inhibitor

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Fluorescent Dye

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155945

    Others Others
    Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM .
    Firefly luciferase-IN-1
  • HY-134956B

    YAP Cancer
    (R)-VT104 is the R-enantiomer of VT104. (R)-VT104 shows an IC50 value of 0.1-1 μΜ for firefly luciferase. VT104 is an orally active and pan-TEAD auto-palmitoylation inhibitor .
    (R)-VT104
  • HY-158256

    Fluorescent Dye Others
    Luciferase-IN-3 (compound 5h) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 3.2 μM, while the inhibitory potency against R. reniformis is not significant .
    Luciferase-IN-3
  • HY-158257

    Fluorescent Dye Others
    Firefly luciferase-IN-4 (CID: 3987260) is an inhibitor of ATP-dependent luciferase (Firefly luciferase). It has nM-level inhibitory activity (pIC< sub>50=6.5) .
    Firefly luciferase-IN-4
  • HY-160870

    Fluorescent Dye Others
    Firefly luciferase-IN-3 (CID: 17087944) is an inhibitor of ATP-dependent luciferase (Firefly luciferase) and has nM-level inhibitory activity against NanoLuc (pIC50=7.5) .
    Firefly luciferase-IN-3
  • HY-160873

    Fluorescent Dye Others
    Firefly luciferase-IN-5 (CID: 16031203) is an inhibitor of ATP-dependent luciferase (Firefly luciferase). It has nM-level inhibitory activity against GRLuc, RLuc8, and RLuc respectively (pIC50=8.5,7.5,5.5) .
    Firefly luciferase-IN-5
  • HY-400902

    YAP Cancer
    YAP/TAZ inhibitor-3 (Compound 24) is a YAP/TAZ inhibitor. YAP/TAZ inhibitor-3 shows firefly luciferase inhibitory activity, with an IC50 < 0.1 μM .
    YAP/TAZ inhibitor-3
  • HY-111429
    YAP/TAZ inhibitor-1
    5+ Cited Publications

    YAP Cancer
    YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay .
    YAP/TAZ inhibitor-1
  • HY-160869

    Fluorescent Dye Others
    Firefly luciferase-IN-2 (compound 5j) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 0.15 μM, while the inhibitory potency against R. reniformis is not significant .
    Firefly luciferase-IN-2
  • HY-160690

    Others Others
    GW632046X is a Fluc (Firefly luciferase) inhibitor with an IC50 value of 0.58 µM .
    GW632046X
  • HY-D1904

    Fluorescent Dye Others
    D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates .
    D-Luciferin 6'-methyl ether
  • HY-115749

    6′-Methoxyluciferin

    Others Others
    D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .
    D-Luciferin 6′-methyl ether

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