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Results for "

Folinic acid

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

8

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17556
    Folinic acid
    Maximum Cited Publications
    10 Publications Verification

    leucovorin

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid
  • HY-17556S1

    Leucovorin-d4 calcium hydrate

    Isotope-Labeled Compounds Cancer
    Folinic acid-d4-1 (Leucovorin-d4-1) calcium hydrate is deuterated labeled Folinic acid (HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.
    Folinic acid-d4 calcium hydrate
  • HY-13664
    Folinic acid calcium
    Maximum Cited Publications
    10 Publications Verification

    Leucovorin calcium; Calcium folinate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium
  • HY-B0080
    Folinic acid calcium salt pentahydrate
    Maximum Cited Publications
    10 Publications Verification

    Leucovorin calcium salt pentahydrate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium salt pentahydrate
  • HY-17556R

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Standard) is the analytical standard of Folinic acid. This product is intended for research and analytical applications. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid (Standard)
  • HY-13664R

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (calcium) (Standard) is the analytical standard of Folinic acid (calcium). This product is intended for research and analytical applications. Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium (Standard)
  • HY-17556A

    Leucovorin disodium

    Endogenous Metabolite Antifolate Cancer
    Folinic acid (Leucovorin) disodium is a biological folic acid and is a forms of vitamin B9. Folinic acid disodium is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity. Folinic acid disodium and Sfluorouracil adjuvant chemotherapy shows effective in colon carcinoma .
    Folinic acid disodium
  • HY-17556B

    Leucovorin calcium hydrate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .
    Folinic acid calcium hydrate
  • HY-137829

    Endogenous Metabolite Others
    5-Methyltetrahydrofolic acid disodium is the metabolite of Folinic acid (Leucovorin) (HY-17556). 5-Methyltetrahydrofolic acid disodium is involved in one-carbon metabolism and the transfer of methyl groups .
    5-Methyltetrahydrofolic acid disodium
  • HY-115429

    6R-Leucovorin calcium; (6R)-Folinic acid calcium

    Others Metabolic Disease
    Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
    Calcium dextrofolinate
  • HY-W653912A

    Isotope-Labeled Compounds Cancer
    Leucovorin-d4 (Leucovorin-d4) calcium hydrate, >90% is a deuterated labeled Folinic acid (Leucovorin, HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .
    Leucovorin-d4 (calcium hydrate), >90%
  • HY-18062
    Pyrimethamine
    5+ Cited Publications

    Pirimecidan; Pirimetamin; RP 4753

    Antifolate Parasite Infection
    Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
    Pyrimethamine
  • HY-13667
    Levoleucovorin Calcium
    2 Publications Verification

    Calcium levofolinate; CL307782

    Antifolate Cancer
    Levoleucovorin Calcium (Calcium levofolinate) is the active form of calcium Folinic acid (HY-13664) and has anti-tumor effects. Levoleucovorin Calcium is also a potentiator of the anti-cancer toxicity of 5-Fluorouracil (HY-90006) .
    Levoleucovorin Calcium
  • HY-18062R

    Antifolate Parasite Infection
    Pyrimethamine (Standard) is the analytical standard of Pyrimethamine. This product is intended for research and analytical applications. Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
    Pyrimethamine (Standard)
  • HY-155846

    Parasite Bacterial Infection
    Antileishmanial agent-22 (compound 15b) is a parasite inhibitor and an antibacterial agent, with antileishmanial, antimalarial, and anti-tubercular activities. Antileishmanial agent-22 inhibits leishmanial (IC50=0.408 μM) based on antifolate mechanism. And, Antileishmanial agent-22 inhibits Folic acid and Folinic acid at 100 μM with inhibitory rates of 88% and 94%, respectively. Antileishmanial agent-22 inhibits P. berghei in vivo and in vitro, with 96.67% suppression under 48.4 μM/kg/day and 0.038 μM (IC50), respectively. Moreover, Antileishmanial agent-22 inhibits M. tuberculosis with MIC of 28.44 μM .
    Antileishmanial agent-22

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