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Results for "

Fungal metabolites

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Metabolite (3) Endogenous Metabolite (49) Fungal (14) Acyltransferase (3) Antibiotic (11) Apoptosis (4) Arp2/3 Complex (1) Autophagy (3) Bacterial (11) Caspase (2) Cathepsin (1) CCR (1) GABA Receptor (2) HCV (1) HDAC (2) HIV (2) HIV Protease (1) Influenza Virus (1) Isotope-Labeled Compounds (2) Mitochondrial Metabolism (1) Neurokinin Receptor (1) NO Synthase (1) Oxidative Phosphorylation (1) PAI-1 (1) Parasite (12) Phosphatase (1) Phosphodiesterase (PDE) (1) PKC (1) PPAR (1) Prostaglandin Receptor (1) Ras (1) Reactive Oxygen Species (1) STAT (2) Tyrosinase (2)
By Research Areas:	Cancer (23) Cardiovascular Disease (4) Endocrinology (2) Infection (58) Inflammation/Immunology (10) Metabolic Disease (8) Neurological Disease (4)

By Targets:

Drug Metabolite (3)

Endogenous Metabolite (49)

Fungal (14)

Acyltransferase (3)

Antibiotic (11)

Apoptosis (4)

Arp2/3 Complex (1)

Autophagy (3)

Bacterial (11)

Caspase (2)

Cathepsin (1)

CCR (1)

GABA Receptor (2)

HCV (1)

HDAC (2)

HIV (2)

HIV Protease (1)

Influenza Virus (1)

Isotope-Labeled Compounds (2)

Mitochondrial Metabolism (1)

Neurokinin Receptor (1)

NO Synthase (1)

Oxidative Phosphorylation (1)

PAI-1 (1)

Parasite (12)

Phosphatase (1)

Phosphodiesterase (PDE) (1)

PKC (1)

PPAR (1)

Prostaglandin Receptor (1)

Ras (1)

Reactive Oxygen Species (1)

STAT (2)

Tyrosinase (2)

By Research Areas:

Cancer (23)

Cardiovascular Disease (4)

Endocrinology (2)

Infection (58)

Inflammation/Immunology (10)

Metabolic Disease (8)

Neurological Disease (4)

115

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Fungal Drug Metabolite Endogenous Metabolite

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111238

Butyrolactone II	Endogenous Metabolite	Infection
Butyrolactone II is a fungal metabolite isolated from Aspergillus flavipes .

HY-P1703

Avellanin B	Endogenous Metabolite	Others
Avellanin B is a fungal metabolite with pressor effect .

HY-N10186

Dibefurin	Phosphatase Endogenous Metabolite	Others
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

HY-N10238

Mycestericin G	Endogenous Metabolite	Inflammation/Immunology
Mycestericin G is a sphingosine-like fungal metabolite that exhibits immunosuppressive activity .

HY-125684

Trichodecenin I	Endogenous Metabolite	Others
Trichodecenin I, a fungal metabolite, is a peptaibol composed of 7 amino acid residues .

HY-N8548

Fellutanine A	Endogenous Metabolite	Infection
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-W714833

2-(2-Hydroxypropionylamino)-benzamide	Endogenous Metabolite	Cardiovascular Disease
2-(2-Hydroxypropionylamino)-benzamide is a fungal metabolite with proangiogenic activities .

HY-125705

Herquline A Herqueline A	Influenza Virus	Infection Cardiovascular Disease
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-125344

Fusarisetin A	Endogenous Metabolite	Infection
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .

HY-118427

Asterriquinol D dimethyl ether	Parasite Endogenous Metabolite	Infection Cancer
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC₅₀ of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits *Tritrichomonas foetus* .

HY-N12877

Ophiobolin H	Bacterial	Infection
Ophiobolin H is a fungal metabolite that can be isolated from Aspergillus ustus. Ophiobolin H inhibits growth of Bacillus subtilis cultures. Ophiobolin H induces hyperacusia in day-old chicks at rates up to 375 mg/kg .

HY-124551

Viridiol	Fungal Antibiotic	Infection
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity .

HY-N10234

Phenylpyropene A	Acyltransferase	Infection
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

HY-N10270

Verrucofortine	Endogenous Metabolite	Others
Verrucofortine, a fungal metabolite, is an alkaloid derived from tryptophan and leucine .

HY-N10220

Paraherquamide E	Endogenous Metabolite Parasite	Infection
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-136767

Cladosporin	Fungal Antibiotic	Infection
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL .

HY-121133

(-)-Cyclopenol	Endogenous Metabolite	Others
(-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .

HY-125411

Berninamycin D	Endogenous Metabolite	Others
Berninamycin D is a cyclic peptide fungal metabolite isolated from ermentation of Streptomyces bernensis .

HY-W145584

D-Iditol	Endogenous Metabolite	Metabolic Disease Cancer
D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity .

HY-N8396

Cerebroside C	Endogenous Metabolite	Infection
Cerebroside C, a sphingolipid, is a fungal metabolite. Cerebroside C licits defense responses in rice .

HY-125060

Viridicatin	Antibiotic Endogenous Metabolite	Infection
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-126603

Asperlactone	Others	Infection
Asperlactone has anti-inflammatory activity. Asperlactone inhibits superoxide anion generation. Asperlactone is a fungal metabolite that can be isolated from isolated from Aspergillus ochraceus .

HY-135154

epi-Aszonalenin A	GABA Receptor	Neurological Disease
epi-Aszonalenin A is a benzodiazepine fungal metabolite originally isolated from Aspergillus novofumigatus. epi-Aszonalenin A can be used as a psychoactive agent .

HY-165114

6-Hydroxyramulosin	Others	Cancer
6-Hydroxyramulosin is a fungal metabolite with antiancer effects. 6-Hydroxyramulosin shows cytotoxic effects against A549 and T24, showing IC₅₀ values of 14.2 µg/mL and 15.3 µg/mL, respectively .

HY-N8349

19,20-Epoxycytochalasin D	Parasite Endogenous Metabolite	Infection Cancer
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N8385

19,20-Epoxycytochalasin C	Parasite Endogenous Metabolite	Infection Cancer
19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N10194

P-orlandin	Parasite Endogenous Metabolite	Infection
P-orlandin, a fungal metabolite, prevents FREP1 from binding to gametocytes or ookinetes. P-orlandin effectively inhibits P. falciparum infection in mosquitoes .

HY-N10228

Gliorosein	Endogenous Metabolite	Infection
Gliorosein is a fungal metabolite isolated from Gliocladium. Gliorosein is isomeric with the quinol but shows a different ultraviolet absorption spectrum .

HY-N10190

Asperaculane B	Parasite Endogenous Metabolite	Infection
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC₅₀ of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC₅₀ of 3 µM, and it is nontoxic to human cells .

HY-N10227

Geodin	PAI-1 Antibiotic	Infection Inflammation/Immunology
Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .

HY-114646

TMC-205	Endogenous Metabolite	Cancer
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter .

HY-N10192

Aculene D	Endogenous Metabolite Bacterial	Infection
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-125170

Galiellalactone	STAT	Cancer
Galiellalactone is a is a small non-toxic and non-mutagenic fungal metabolite, a selective inhibitor of STAT3 signaling, with an IC₅₀ of 250-500 nM. Galiellalactone can be used to research castration-resistant prostate cancer .

HY-P3107

Homodestcardin	Endogenous Metabolite	Inflammation/Immunology
Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC₅₀ value of 0.86 μM .

HY-136901

Fusarochromanone FC-101	Reactive Oxygen Species	Cardiovascular Disease Cancer
Fusarochromanone (FC-101) is a fungal metabolite with potent anti-angiogenic and anti-cancer activity . Fusarochromanone-activated JNK pathway is attributed to induction of reactive oxygen species (ROS) .

HY-119552

Acetylaszonalenin LL-S490β	Endogenous Metabolite Neurokinin Receptor	Neurological Disease
Acetylaszonalenin, a prenylated indole derivative, is a fungal metabolite.Acetylaszonalenin is a potent neurokinin-1 (NK1) receptor antagonist. Acetylaszonalenin shows inhibition of [ ³H]-SP binding to human astrocytoma cells with a K_i of 170 μM .

HY-N10322

2-Hydroxyemodin	Drug Metabolite	Others
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

HY-N6735

Apicidin 3 Publications Verification OSI 2040	HDAC Parasite	Infection Cancer
Apicidin (OSI 2040) is a *fungal* metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-120607

Chevalone C	Parasite	Infection Cancer
Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC₅₀ value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines .

HY-126989

19-O-Acetylchaetoglobosin A	Arp2/3 Complex	Cancer
19-O-Acetylchaetoglobosin A, a cytochalasan alkaloid, is a fungal metabolite originally isolated from C. globosum that has actin polymerization inhibitory and cytotoxic activities. 19-O-Acetylchaetoglobosin A is cytotoxic to HeLa cervical cancer cells .

HY-W099579

Kojic acid dipalmitate Kojic dipalmitate	Tyrosinase	Endocrinology
Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-163113

Anticancer agent 180	Others	Cancer
Anticancer agent 180 (compound 4) is a secondary metabolite present in fungal strains and extracted through physical interaction with Streptomyces sp. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells .

HY-W099579R

Kojic acid dipalmitate (Standard)	Tyrosinase	Endocrinology
Kojic acid dipalmitate (Standard) is the analytical standard of Kojic acid dipalmitate. This product is intended for research and analytical applications. Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-N6798

Myriocin 4 Publications Verification Thermozymocidin; ISP-I	HCV Antibiotic	Infection
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC₅₀ of 3.5 μg/mL for inhibiting HCV infection .

HY-120733

Calpinactam FKI-4905	Bacterial Endogenous Metabolite	Infection Inflammation/Immunology
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-129319

Valinotricin	Endogenous Metabolite	Others
Valinotricin is a fungal metabolite .

HY-117713

Cycloechinulin	Endogenous Metabolite	Others
Cycloechinulin is a diketopiperazine fungal metabolite .

HY-N10282

Isodihydroauroglaucin	Fungal Bacterial Endogenous Metabolite	Infection
Isodihydroauroglaucin, a fungal metabolite, shows antibacterial activity .

HY-N6217

F-14329	Endogenous Metabolite	Others
F-14329 is a tetramic acid fungal metabolite .

HY-125596

Lachnumon	Parasite	Infection
Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .

Cat. No.	Product Name

HY-L0117V

Asinex Macrocycles for Glycomimetics Library

1,412 compounds

Glycomimetics are designed to mimic the structure of natural carbohydrates and modulate their disease-related functions. Macrocyclic glycomimetics are an extremely interesting class of glycomimetics as they occupy space between small and macro molecules. Macrocyclic glycomimetics are mostly represented by naturally occurring molecules derived from marine microorganisms and bacterial or fungal metabolites.

Cat. No.	Product Name	Target	Research Area

HY-P3107

Homodestcardin	Endogenous Metabolite	Inflammation/Immunology
Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC₅₀ value of 0.86 μM .

HY-P2228

Chlamydocin	HDAC Apoptosis	Cancer
Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC₅₀ of 1.3 nM. Chlamydocin exhibits potent antiproliferative and anticancer activities. Chlamydocin induces apoptosis by activating caspase-3 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-111238

Butyrolactone II	Infection Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields	Endogenous Metabolite
Butyrolactone II is a fungal metabolite isolated from Aspergillus flavipes .

HY-P1703

Avellanin B	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Avellanin B is a fungal metabolite with pressor effect .

HY-N10186

Dibefurin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Phosphatase Endogenous Metabolite
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

HY-N10238

Mycestericin G	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
Mycestericin G is a sphingosine-like fungal metabolite that exhibits immunosuppressive activity .

HY-125684

Trichodecenin I	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Trichodecenin I, a fungal metabolite, is a peptaibol composed of 7 amino acid residues .

HY-N8548

Fellutanine A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-W714833

2-(2-Hydroxypropionylamino)-benzamide	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
2-(2-Hydroxypropionylamino)-benzamide is a fungal metabolite with proangiogenic activities .

HY-125705

Herquline A Herqueline A	Cardiovascular Disease Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Influenza Virus
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-125344

Fusarisetin A	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .

HY-118427

Asterriquinol D dimethyl ether	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Parasite Endogenous Metabolite
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC₅₀ of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits *Tritrichomonas foetus* .

HY-N12877

Ophiobolin H	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Ophiobolin H is a fungal metabolite that can be isolated from Aspergillus ustus. Ophiobolin H inhibits growth of Bacillus subtilis cultures. Ophiobolin H induces hyperacusia in day-old chicks at rates up to 375 mg/kg .

HY-124551

Viridiol	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Fungal Antibiotic
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity .

HY-N10234

Phenylpyropene A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Acyltransferase
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

HY-N10270

Verrucofortine	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Verrucofortine, a fungal metabolite, is an alkaloid derived from tryptophan and leucine .

HY-N10220

Paraherquamide E	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite Parasite
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-136767

Cladosporin	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Fungal Antibiotic
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL .

HY-121133

(-)-Cyclopenol	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Marine natural products Other Diseases Disease Research Fields Marine microorganism	Endogenous Metabolite
(-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .

HY-125411

Berninamycin D	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Disease Research Fields	Endogenous Metabolite
Berninamycin D is a cyclic peptide fungal metabolite isolated from ermentation of Streptomyces bernensis .

HY-W145584

D-Iditol	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Endogenous Metabolite
D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity .

HY-N8396

Cerebroside C	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite
Cerebroside C, a sphingolipid, is a fungal metabolite. Cerebroside C licits defense responses in rice .

HY-125060

Viridicatin	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Quinoline Alkaloids Disease Research Fields	Antibiotic Endogenous Metabolite
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-135154

epi-Aszonalenin A	Alkaloids Microorganisms Source classification	GABA Receptor
epi-Aszonalenin A is a benzodiazepine fungal metabolite originally isolated from Aspergillus novofumigatus. epi-Aszonalenin A can be used as a psychoactive agent .

HY-N8349

19,20-Epoxycytochalasin D	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite Endogenous Metabolite
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N8385

19,20-Epoxycytochalasin C	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite Endogenous Metabolite
19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N10194

P-orlandin	Infection Microorganisms Classification of Application Fields Source classification Coumarins Phenols Polyphenols Phenylpropanoids Disease Research Fields	Parasite Endogenous Metabolite
P-orlandin, a fungal metabolite, prevents FREP1 from binding to gametocytes or ookinetes. P-orlandin effectively inhibits P. falciparum infection in mosquitoes .

HY-N10228

Gliorosein	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Disease Research Fields	Endogenous Metabolite
Gliorosein is a fungal metabolite isolated from Gliocladium. Gliorosein is isomeric with the quinol but shows a different ultraviolet absorption spectrum .

HY-N10190

Asperaculane B	Infection Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Endogenous metabolite Disease Research Fields	Parasite Endogenous Metabolite
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC₅₀ of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC₅₀ of 3 µM, and it is nontoxic to human cells .

HY-N10227

Geodin	Human Gut Microbiota Metabolites Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields Inflammation/Immunology	PAI-1 Antibiotic
Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .

HY-114646

TMC-205	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids Cancer	Endogenous Metabolite
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-P3107

Homodestcardin	Structural Classification Microorganisms Classification of Application Fields Cyclopeptides Source classification Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC₅₀ value of 0.86 μM .

HY-136901

Fusarochromanone FC-101	Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Reactive Oxygen Species
Fusarochromanone (FC-101) is a fungal metabolite with potent anti-angiogenic and anti-cancer activity . Fusarochromanone-activated JNK pathway is attributed to induction of reactive oxygen species (ROS) .

HY-119552

Acetylaszonalenin LL-S490β	Alkaloids Microorganisms Source classification Indole Alkaloids	Endogenous Metabolite Neurokinin Receptor
Acetylaszonalenin, a prenylated indole derivative, is a fungal metabolite.Acetylaszonalenin is a potent neurokinin-1 (NK1) receptor antagonist. Acetylaszonalenin shows inhibition of [ ³H]-SP binding to human astrocytoma cells with a K_i of 170 μM .

HY-N10322

2-Hydroxyemodin	Quinones other families Classification of Application Fields Anthraquinones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Drug Metabolite
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

HY-N6735

Apicidin 3 Publications Verification OSI 2040	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Anti-parasitic Disease Research Anticancer Disease Research Fields Other Antibiotics	HDAC Parasite
Apicidin (OSI 2040) is a *fungal* metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-120607

Chevalone C	Infection Triterpenes Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields	Parasite
Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC₅₀ value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines .

HY-126989

19-O-Acetylchaetoglobosin A	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	Arp2/3 Complex
19-O-Acetylchaetoglobosin A, a cytochalasan alkaloid, is a fungal metabolite originally isolated from C. globosum that has actin polymerization inhibitory and cytotoxic activities. 19-O-Acetylchaetoglobosin A is cytotoxic to HeLa cervical cancer cells .

HY-163113

Anticancer agent 180	Structural Classification Microorganisms Source classification Phenols	Others
Anticancer agent 180 (compound 4) is a secondary metabolite present in fungal strains and extracted through physical interaction with Streptomyces sp. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells .

HY-N6798

Myriocin 4 Publications Verification Thermozymocidin; ISP-I	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	HCV Antibiotic
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC₅₀ of 3.5 μg/mL for inhibiting HCV infection .

HY-120733

Calpinactam FKI-4905	Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology	Bacterial Endogenous Metabolite
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-129319

Valinotricin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Valinotricin is a fungal metabolite .

HY-117713

Cycloechinulin	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Cycloechinulin is a diketopiperazine fungal metabolite .

HY-N10282

Isodihydroauroglaucin	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Disease Research Fields	Fungal Bacterial Endogenous Metabolite
Isodihydroauroglaucin, a fungal metabolite, shows antibacterial activity .

HY-N6217

F-14329	Alkaloids Monophenols Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Phenols Disease Research Fields	Endogenous Metabolite
F-14329 is a tetramic acid fungal metabolite .

HY-125596

Lachnumon	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Parasite
Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .

HY-N10257

Burnettramic acid A aglycone	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Burnettramic acid A aglycone is a fungal metabolite found in Aspergillus burnettii .

HY-N8325

Phomosine D	Structural Classification Microorganisms Source classification Phenols Polyphenols	Endogenous Metabolite
Phomosine D is a fungal metabolite originally isolated from Phomopsis.

HY-N7718

(−)-Rugulosin	Structural Classification Flavonoids Microorganisms Source classification Other Flavonoids	Endogenous Metabolite
(−)-Rugulosin is a fungal metabolite and an orally active antiinfluenzal agent .

HY-119328

Pestalotin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Pestalotin, a fungal lactone, is a secondary metabolite of endophytic fungus Pestalotiopsis microspore .

HY-116290

Zaragozic acid A 1 Publications Verification Squalestatin S1	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase .

Cat. No.	Product Name	Chemical Structure

HY-W145584S

D-Iditol-13C
D-Iditol- ¹³C is the ¹³C labeled D-Iditol. D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity[1][2][3].

HY-N6801S

Nivalenol-13C15

Nivalenol- ¹³C₁₅ is the ¹³C labeled Nivalenol (HY-N6801) . Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product . Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect .

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Fungal metabolites

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Isotope-Labeled Compounds

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