2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Voriconazole N-oxide hydrochloride

Voriconazole N-oxide hydrochloride  (Synonyms: Voriconazole oxynitride hydrochloride)

Cat. No.: HY-137989A Purity: 99.52%
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Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity.

For research use only. We do not sell to patients.

Voriconazole N-oxide hydrochloride Chemical Structure

Voriconazole N-oxide hydrochloride Chemical Structure

Size Price Stock Quantity
5 mg USD 220 In-stock
10 mg USD 360 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Voriconazole N-oxide hydrochloride:

Voriconazole N-oxide hydrochloride Related Antibodies

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Description

Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity[1].

IC50 & Target

others
Molecular Weight

401.77

Formula

C16H15ClF3N5O2
Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](C1=NC=[N+]([O-])C=C1F)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (311.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4890 mL 12.4449 mL 24.8899 mL
5 mM 0.4978 mL 2.4890 mL 4.9780 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4890 mL 12.4449 mL 24.8899 mL 62.2247 mL
5 mM 0.4978 mL 2.4890 mL 4.9780 mL 12.4449 mL
10 mM 0.2489 mL 1.2445 mL 2.4890 mL 6.2225 mL
15 mM 0.1659 mL 0.8297 mL 1.6593 mL 4.1483 mL
20 mM 0.1244 mL 0.6222 mL 1.2445 mL 3.1112 mL
25 mM 0.0996 mL 0.4978 mL 0.9956 mL 2.4890 mL
30 mM 0.0830 mL 0.4148 mL 0.8297 mL 2.0742 mL
40 mM 0.0622 mL 0.3111 mL 0.6222 mL 1.5556 mL
50 mM 0.0498 mL 0.2489 mL 0.4978 mL 1.2445 mL
60 mM 0.0415 mL 0.2074 mL 0.4148 mL 1.0371 mL
80 mM 0.0311 mL 0.1556 mL 0.3111 mL 0.7778 mL
100 mM 0.0249 mL 0.1244 mL 0.2489 mL 0.6222 mL
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Voriconazole N-oxide hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Voriconazole N-oxideVoriconazole oxynitrideDrug MetaboliteAntibioticVoriconazole MetaboliteInhibitorinhibitorinhibit

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