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Isoforms Recommended: HDAC9
Results for "

HDAC9

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112719
    BRD 4354
    3 Publications Verification

    		 HDAC Cancer
    BRD 4354 is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively.
    BRD 4354
  • HY-18361
    TMP195
    Maximum Cited Publications
    14 Publications Verification

    		 HDAC Cancer
    TMP195 is a selective class IIa histone deacetylase (HDAC) inhibitor with Kis of 59, 60, 26, 15 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
    TMP195
  • HY-18360
    TMP269
    10+ Cited Publications

    		 HDAC Cancer
    TMP269 is a novel and selective class IIa histone deacetylase (HDAC) inhibitor with IC50s of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
    TMP269
  • HY-119939
    CHDI-390576

    		HDAC Cancer
    CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histone deacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform .
    CHDI-390576
  • HY-RS06088
    HDAC9 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HDAC9 Human Pre-designed siRNA Set A contains three designed siRNAs for HDAC9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HDAC9 Human Pre-designed siRNA Set A
    HDAC9 Human Pre-designed siRNA Set A
  • HY-RS06089
    Hdac9 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Hdac9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hdac9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Hdac9 Mouse Pre-designed siRNA Set A
    Hdac9 Mouse Pre-designed siRNA Set A
  • HY-RS06090
    HDAC9 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HDAC9 Rat Pre-designed siRNA Set A contains three designed siRNAs for HDAC9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HDAC9 Rat Pre-designed siRNA Set A
    HDAC9 Rat Pre-designed siRNA Set A
  • HY-169259
    HDAC9-IN-1

    		HDAC Cancer
    HDAC9-IN-1 (Compound 7g) is a potent HDAC9 inhibitor, with an IC50 of 40 nM. HDAC9-IN-1 significantly inhibits several human cancer cells, induces apoptosis, modulates caspase-related proteins as well as p38, and causes DNA damage .
    HDAC9-IN-1
  • HY-112719B
    BRD 4354 ditrifluoroacetate

    		HDAC Cancer
    BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively .
    BRD 4354 ditrifluoroacetate
  • HY-152226
    MC2590

    		HDAC Apoptosis Cancer
    MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is a inhibitor of HDAC1-3, -6, -8, and -10 (class I/IIb-selective inhibitor) with IC50s of 0.015 μM-0.156 μM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 μM-3.98 μM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction .
    MC2590
  • HY-114548
    Ebselen oxide

    		Guanylate Cyclase Infection
    Ebselen oxide, the selenone analogue of Ebselen, covalently modifies diguanylate cyclase (DGC) to inhibit c-di-GMP-receptor interactions and reduces DGC activity. Ebselen oxide also inhibits alginate production (IC50=14 μM) by Pseudomonas aeruginosa. Ebselen oxide inhibits HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9 (IC50 ranging from 0.2 to 4.7 μM) .
    Ebselen oxide
  • HY-152225
    MC2625

    		HDAC Apoptosis Cancer
    MC2625 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2625 show selective HDAC3 and HDAC6 inhibition with IC50s of 80 nM and 11 nM. MC2625 increases acetyl-H3 and acetyl-tubulin levels and inhibits cancer stem cells (CSCs) growth by apoptosis induction .
    MC2625

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