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Results for "

HL2/3

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-143277
    HL-2

    		Ligands for Target Protein for PROTAC Cancer
    HL-2 is a ligand of the target protein PI3K kinase of HL-8 (HY-143275), which can be used for PROTAC synthesis .
    HL-2
  • HY-P10875
    HL2-m5

    		Hedgehog Cancer
    HL2-m5 is the inhibitor for the interaction between sonic hedgehog/patched (Shh/PTCH1) with Kd of 170 nM for Shh. HL2-m5 inhibits activation of Hedgehog signaling pathway and transcription of Gli-controlled gene with an IC50 of 230 nM .
    HL2-m5
  • HY-155248
    HL23

    		HDAC Cancer
    HL23 is a histone deacetylase (HDAC) inhibitor with activity against hepatocellular carcinoma (HCC). HL23 enhances acetylation of the TXNIP promoter and upregulates TXNIP expression, thereby mediating potassium channel activity and triggering TXNIP-dependent potassium deprivation. HL23 inhibits HCC progression and metastasis and has a synergistic effect with Sorafenib (HY-10201) and is more potent than Sorafenib+Vorinostat (HY-10221) .
    HL23

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