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Human respiratory syncytial virus

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Influenza Virus (1) RSV (7) 5-HT Receptor (1) Apoptosis (1) Calcium Channel (1) FLAP (1) HSV (1) MDM-2/p53 (1) SARS-CoV (1)
By Research Areas:	Infection (7) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Targets Recommended: RSV Influenza Virus Dengue virus Virus Protease

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99209

Motavizumab MEDI-524	RSV	Infection
Motavizumab (MEDI-524) is an anti-human RSV (respiratory **syncytial virus*) monoclonal antibody. Motavizumab can be used in respiratory* syncytial virus infection in high-risk infants research .

HY-P99756

Nirsevimab MEDI8897	RSV	Infection
Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC₅₀ values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .

HY-P99804

Clesrovimab MK1654	RSV	Infection
Clesrovimab (MK1654) is a fully human, anti-RSV fusion (RSV F) glycoprotein monoclonal antibody. Clesrovimab has the potential for the research of respiratory syncytial virus infection .

HY-14460

AM679	FLAP	Inflammation/Immunology
AM679 is a potent, selective 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC₅₀ of 2 nM in a human FLAP membrane binding assay. AM679 markedly reduces the respiratory syncytial virus-driven ocular pathology as well as the synthesis of cysteinyl leukotrienes (CysLTs) in the eye .

HY-W013605A

4-Methoxycinnamaldehyde p-Methoxycinnamaldehyde	RSV	Infection
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC₅₀ of 0.055 μg/mL .

HY-N6771

Cyclopiazonic acid 3 Publications Verification	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV	Infection
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-162701

Antiviral agent 58	SARS-CoV Influenza Virus RSV HSV	Infection
Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2 .

HY-169313

HRSV/HMPV-IN-1	RSV	Infection
HRSV/HMPV-IN-1 (compound 3) is a HRSV/HMPV inhibitor with the EC₅₀ values of ＜ 0.2 μM and ＜ 0.5 μM for human RSV-A and human MPV A2 TN/94-49, respectively. HRSV/HMPV-IN-1 can be used for study of bronchiolitis and pneumonia .

Cat. No.	Product Name	Target	Research Area

HY-P99209

Motavizumab MEDI-524	RSV	Infection
Motavizumab (MEDI-524) is an anti-human RSV (respiratory **syncytial virus*) monoclonal antibody. Motavizumab can be used in respiratory* syncytial virus infection in high-risk infants research .

HY-P99756

Nirsevimab MEDI8897	RSV	Infection
Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC₅₀ values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .

HY-P99804

Clesrovimab MK1654	RSV	Infection
Clesrovimab (MK1654) is a fully human, anti-RSV fusion (RSV F) glycoprotein monoclonal antibody. Clesrovimab has the potential for the research of respiratory syncytial virus infection .

4-Methoxycinnamaldehyde p-Methoxycinnamaldehyde	Infection Structural Classification Classification of Application Fields Araceae Ketones, Aldehydes, Acids Source classification Acorus gramineus Soland. Plants Disease Research Fields	RSV
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC₅₀ of 0.055 μg/mL .

Cyclopiazonic acid 3 Publications Verification	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Disease Research Fields Indole Alkaloids	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

Species:	Virus (9)
Tag:	His (9) B2M (1)
Source:	HEK293 (3) Sf9 insect cells (5) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P75182

	Fusion glycoprotein F0/F Protein, HRSV (sf9, His) Human respiratory syncytial virus Fusion glycoprotein/RSV-F Protein; F Protein; HRSVgp08 Protein	Virus	Sf9 insect cells
	The fusion glycoprotein F0/F protein is initially an inactive precursor that is cleaved by furin-like proteases to produce the mature F1 and F2 fusion glycoproteins.As a class I viral fusion protein, it undergoes prefusion, prehairpin, and postfusion states.Fusion glycoprotein F0/F Protein, HRSV (sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75814

	Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (95% Homology)	Virus	HEK293
	A glycoprotein/G protein critical in the immune response forms the interleukin-31 receptor with OSMR.This receptor activates STAT3 and, to a lesser extent, STAT1 and STAT5, playing a critical role in skin immunity and mediating IL31-induced itch, possibly involving TRPA1 and TRPV1.Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) is the recombinant Virus-derived Glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag.

HY-P71478

	Fusion glycoprotein F0/F Protein, HRSVA (His, B2M) Fusion glycoprotein F0; Protein F; Interchain peptide; Fusion glycoprotein F2; Human respiratory syncytial virus A Fusion glycoprotein F0	Virus	E. coli
	The fusion glycoprotein F0/F protein is initially an inactive precursor that is cleaved by furin-like proteases to produce the mature F1 and F2 fusion glycoproteins. As a class I viral fusion protein, it undergoes prefusion, prehairpin, and postfusion states. Fusion glycoprotein F0/F Protein, HRSVA (His, B2M) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by E. coli , with N-B2M, N-6*His labeled tag. The total length of Fusion glycoprotein F0/F Protein, HRSVA (His, B2M) is 503 a.a., with molecular weight of ~69.9 kDa.

HY-P75818

	glycoprotein/G Protein, HRSV (258a.a, HEK293, His) Human respiratory syncytial virus (RSV) Glycoprotein G Protein	Virus	HEK293
	RSV G protein is a type II, highly glycosylated membrane protein with a full length of 292-319 amino acids (AA), an intracellular cytoplasmic tail (AA 1-37), and a transmembrane domain (AA 38 -66) and the extracellular domain ending in its carboxyl terminus.The RSV G protein has broad effects on the biology of RSV infection as well as host immune responses and infection-associated diseases.glycoprotein/G Protein, HRSV (HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag.

HY-P75812

	glycoprotein/G Protein, HRSV (sf9, His) Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (93% Homology)	Virus	Sf9 insect cells
	A glycoprotein/G protein critical in the immune response forms the interleukin-31 receptor with OSMR.This receptor activates STAT3 and, to a lesser extent, STAT1 and STAT5, playing a critical role in skin immunity and mediating IL31-induced itch, possibly involving TRPA1 and TRPV1.glycoprotein/G Protein, HRSV (sf9, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75816

	Fusion glycoprotein F0/F Protein, HRSV (AFX60213, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F Protein	Virus	Sf9 insect cells
	F0/F is a class of viral fusion proteins that, as an inactive precursor, are cleaved by a furfurin-like protease at two sites to produce mature F1 and F2 fusion glycoproteins.The F protein can mediate cell-cell fusion, lead to syncytial formation, and trigger p53-dependent apoptosis in the later stages of infection.Fusion glycoprotein F0/F Protein, HRSV (AFX60213, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75817

	Fusion glycoprotein F0/F Protein, HRSV (AHX57537, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F Protein	Virus	Sf9 insect cells
	F0/F is a class of viral fusion proteins that, as an inactive precursor, are cleaved by a furfurin-like protease at two sites to produce mature F1 and F2 fusion glycoproteins.The F protein can mediate cell-cell fusion, lead to syncytial formation, and trigger p53-dependent apoptosis in the later stages of infection.Fusion glycoprotein F0/F Protein, HRSV (AHX57537, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75813

	glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (93% Homology)	Virus	HEK293
	A glycoprotein/G protein critical in the immune response forms the interleukin-31 receptor with OSMR.This receptor activates STAT3 and, to a lesser extent, STAT1 and STAT5, playing a critical role in skin immunity and mediating IL31-induced itch, possibly involving TRPA1 and TRPV1.glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag.

HY-P75815

	Fusion glycoprotein F0/F Protein, HRSV (P11209, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F (Strain RSS-2) Protein	Virus	Sf9 insect cells
	The fusion glycoprotein F0/F protein is cleaved to generate mature F1 and F2 fusion glycoproteins.It functions as a viral fusion protein, promoting the fusion of virus and cell membranes through different state transitions.Fusion glycoprotein F0/F Protein, HRSV (P11209, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

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Human respiratory syncytial virus

Inhibitors & Agonists

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

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