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Iodoacetamide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Biochemical Assay Reagents (4) CXCR (2) DNA Alkylator/Crosslinker (2) Fluorescent Dye (11) GCGR (2) Isotope-Labeled Compounds (2) Melanocortin Receptor (1) Neuropeptide Y Receptor (3) Parasite (1) PROTAC Linkers (6) Somatostatin Receptor (1) TRP Channel (1)
By Research Areas:	Cancer (12) Infection (1) Inflammation/Immunology (1) Metabolic Disease (5) Neurological Disease (5)
Click Chemistry:	PROTAC Synthesis (2) Azide (2) Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-34477

2-Iodoacetamide 3 Publications Verification Iodoacetamide	DNA Alkylator/Crosslinker	Others
2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics .

HY-34477S1

*2-Iodoacetamide-d4* Iodoacetamide-d₄	DNA Alkylator/Crosslinker	Others
2-Iodoacetamide-d₄ is the deuterium labeled 2-Iodoacetamide . 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics .

HY-134687

Iodoacetamide-PEG5-azide	PROTAC Linkers	Cancer
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140857

Iodoacetamide-PEG3-azide	PROTAC Linkers	Cancer
Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136205

IA-Alkyne Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide	TRP Channel	Infection Inflammation/Immunology
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-150230

Desthiobiotin-Iodoacetamide	ADC Linker	Cancer
Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis .

HY-123749

Tetramethylrhodamine-5-iodoacetamide 5-TMRIA	Fluorescent Dye	Others
Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues. Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) can be used to covalently label DNA fragments .

HY-134738

Iodoacetamide-PEG5-NH-Boc	PROTAC Linkers	Cancer
Iodoacetamide-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-134688

Iodoacetamide-PEG5-NH2	PROTAC Linkers	Cancer
Iodoacetamide-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-D1921

ATTO 390 iodoacetamide	Fluorescent Dye	Others
ATTO 390 iodoacetamide is the iodoacetamide derivative of ATTO 390, the maximum excitation/emission wavelength: 390/476 nm.

HY-W719403

*N-(4-Hydroxyphenyl)-2-iodoacetamide-d6*	Isotope-Labeled Compounds	Others
N-(4-Hydroxyphenyl)-2-iodoacetamide-d₆ is the deuterium labeled N-(4-Hydroxyphenyl)-2-iodoacetamide (HY-W719402).

HY-W711386

*N-(4-Hydroxyphenethyl)-2-iodoacetamide-d4*	Isotope-Labeled Compounds	Others
N-(4-Hydroxyphenethyl)-2-iodoacetamide-d₄ is the deuterium labeled N-(4-Hydroxyphenethyl)-2-iodoacetamide (HY-W711377).

HY-134718

Glycocholic acid-PEG10-iodoacetamide	PROTAC Linkers	Cancer
Glycocholic acid-PEG10-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-143205

Desthiobiotin polyethyleneoxide iodoacetamide	Biochemical Assay Reagents	Cancer
Desthiobiotin polyethyleneoxide iodoacetamide is useful for cysteine labeling in chemoproteomic experiments .

HY-W559951

*4-(N-Iodoacetamide)benzophenone*	Biochemical Assay Reagents	Others
4-(N-Iodoacetamide)benzophenone is a biochemical reagent.

HY-140941

Biotin-PEG2-C2-iodoacetamide	PROTAC Linkers	Cancer
Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-149182

*Lucifer yellow iodoacetamide* dipotassium**	Fluorescent Dye	Others
Lucifer yellow iodoacetamide dipotassium is a thiol-reactive fluorescent tracer.

HY-W800828

Iodoacetamido-PEG3-NHS ester	Biochemical Assay Reagents	Others
Iodoacetamido-PEG3-NHS ester is a PEG reagent containing an Iodoacetamide group and a Boc-protected amino group. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-D1981

ATTO 633 iodacetamid	Fluorescent Dye	Others
ATTO 633 Iodacetamid is an iodoacetamide derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.

HY-W190947

Iodoacetamido-PEG8-acid	Biochemical Assay Reagents	Others
Iodoacetamido-PEG8-acid is a PEG reagent containing an Iodoacetamide group and a carboxlic acid moiety. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group.

HY-D2080

ATTO 665 iodacetamid	Fluorescent Dye	Others
ATTO 665 iodacetamid is an iodoacetamide derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.

HY-D2036

ATTO 550 iodacetamid	Fluorescent Dye	Others
ATTO 550 iodacetamid is an iodoacetamide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.

HY-D2068

ATTO 680 iodacetamid	Fluorescent Dye	Others
ATTO 680 iodacetamid is an iodoacetamide derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.

HY-D2009

ATTO 565 iodacetamid	Fluorescent Dye	Others
ATTO 565 iodacetamid is an iodoacetamide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.

HY-D1945

ATTO 590 iodacetamid	Fluorescent Dye	Others
ATTO 590 Iodacetamid is an iodoacetamide derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.

HY-D2052

ATTO 532 iodacetamid	Fluorescent Dye	Others
ATTO 532 iodacetamid is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 iodacetamid is an iodoacetamide derivative of ATTO 532, which can be used to label proteins or antibodies.

HY-P3567

*(p-Iodo-Phe7)-ACTH (4-10)*	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P2231A

Cotadutide acetate 1 Publications Verification MEDI0382 acetate	GCGR	Metabolic Disease
Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC₅₀ values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .

HY-P10026

Nisotirostide LY-3457263	Neuropeptide Y Receptor	Metabolic Disease
Nisotirotide (LY-3457263) is a subcutaneous injectable NPY2 receptor agonist. By mimicking peptide YY (PYY), Nisotirotide inhibits appetite and can be used in the research of diseases such as obesity and diabetes .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P2231

Cotadutide 1 Publications Verification MEDI0382	GCGR	Metabolic Disease
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC₅₀ values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

Tetramethylrhodamine-5-iodoacetamide 5-TMRIA	Dyes
Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues. Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) can be used to covalently label DNA fragments .

ATTO 390 iodoacetamide	Fluorescent Dyes/Probes
ATTO 390 iodoacetamide is the iodoacetamide derivative of ATTO 390, the maximum excitation/emission wavelength: 390/476 nm.

*Lucifer yellow iodoacetamide* dipotassium**	Fluorescent Dyes/Probes
Lucifer yellow iodoacetamide dipotassium is a thiol-reactive fluorescent tracer.

ATTO 633 iodacetamid	Fluorescent Dyes/Probes
ATTO 633 Iodacetamid is an iodoacetamide derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.

ATTO 665 iodacetamid	Fluorescent Dyes/Probes
ATTO 665 iodacetamid is an iodoacetamide derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.

ATTO 550 iodacetamid	Fluorescent Dyes/Probes
ATTO 550 iodacetamid is an iodoacetamide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.

ATTO 680 iodacetamid	Fluorescent Dyes/Probes
ATTO 680 iodacetamid is an iodoacetamide derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.

ATTO 565 iodacetamid	Fluorescent Dyes/Probes
ATTO 565 iodacetamid is an iodoacetamide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.

Cat. No.	Product Name	Target	Research Area

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P2231A

Cotadutide acetate 1 Publications Verification MEDI0382 acetate	GCGR	Metabolic Disease
Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC₅₀ values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .

HY-P10026

Nisotirostide LY-3457263	Neuropeptide Y Receptor	Metabolic Disease
Nisotirotide (LY-3457263) is a subcutaneous injectable NPY2 receptor agonist. By mimicking peptide YY (PYY), Nisotirotide inhibits appetite and can be used in the research of diseases such as obesity and diabetes .

HY-P2231

Cotadutide 1 Publications Verification MEDI0382	GCGR	Metabolic Disease
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC₅₀ values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .

HY-P3567

*(p-Iodo-Phe7)-ACTH (4-10)*	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P4070

Insulin icodec	Peptides	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes .

Cat. No.	Product Name	Chemical Structure

HY-34477S1

*2-Iodoacetamide-d4*
2-Iodoacetamide-d₄ is the deuterium labeled 2-Iodoacetamide . 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics .

HY-W719403

*N-(4-Hydroxyphenyl)-2-iodoacetamide-d6*
N-(4-Hydroxyphenyl)-2-iodoacetamide-d₆ is the deuterium labeled N-(4-Hydroxyphenyl)-2-iodoacetamide (HY-W719402).

HY-W711386

*N-(4-Hydroxyphenethyl)-2-iodoacetamide-d4*
N-(4-Hydroxyphenethyl)-2-iodoacetamide-d₄ is the deuterium labeled N-(4-Hydroxyphenethyl)-2-iodoacetamide (HY-W711377).

Cat. No.	Product Name		Classification

HY-134687

Iodoacetamide-PEG5-azide		Azide PROTAC Synthesis
Iodoacetamide-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140857

Iodoacetamide-PEG3-azide		Azide PROTAC Synthesis
Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Iodoacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136205

IA-Alkyne Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide		Alkynes
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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