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Results for "

MICA

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Inhibitory Antibodies

7

Recombinant Proteins

1

Antibodies

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS08424
    MICA Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MICA Human Pre-designed siRNA Set A contains three designed siRNAs for MICA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MICA Human Pre-designed siRNA Set A
    MICA Human Pre-designed siRNA Set A
  • HY-155311
    NKG2D-IN-1

    		Others Inflammation/Immunology
    NKG2D-IN-1 (compound 21) is a natural killer group 2D receptor (NKG2D) inhibitor with IC50s of 0.3 µM and 0.7 µM in NKG2D/MICA and ULBP6 TR-FRET assays, respectively .
    NKG2D-IN-1
  • HY-155312
    NKG2D-IN-2

    		Others Cancer
    NKG2D-IN-2 (compound 47) is a natural killer group 2D receptor (NKG2D) inhibitor with IC50s of 0.1 µM and 0.2 µM in NKG2D/MICA and ULBP6 TR-FRET assays, respectively .
    NKG2D-IN-2
  • HY-101780A
    Tinostamustine hydrochloride

    EDO-S101 hydrochloride; NL-101 hydrochloride

    		 HDAC Cancer
    Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice .
    Tinostamustine hydrochloride
  • HY-151782
    H-(Gly)3-Lys(N3)-OH

    		ADC Linker Others
    The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    H-(Gly)3-Lys(N3)-OH

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