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MRL871

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ROR (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*MRL-871* 1 Publications Verification	ROR	Cancer
MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC₅₀ of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells .

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