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Results for "

Naproxen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (5) COX (13) iGluR (2) Isotope-Labeled Compounds (3) Trk Receptor (2)
By Research Areas:	Cancer (9) Inflammation/Immunology (14) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15030

*Naproxen* 3 Publications Verification (S)-Naproxen	COX Autophagy	Inflammation/Immunology Cancer
Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-15030A

Naproxen sodium 3 Publications Verification	Autophagy COX	Inflammation/Immunology Cancer
Naproxen sodium is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-19675

Naproxen etemesil LT-NS 001; MX 1094	COX	Inflammation/Immunology
Naproxen etemesil is a lipophilic, non-acidic, inactive proagent of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-B2121

6-Methoxy-2-naphthoic acid Naproxen impurity O	iGluR	Neurological Disease
6-Methoxy-2-naphthoic acid is an NMDA receptor modulator extracted from patent WO 2012019106 A2.

HY-W121901

Naproxen glucuronide (S)-Naproxen-β-D-glucuronide	COX	Inflammation/Immunology
Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .

HY-15030R

Naproxen (Standard) (S)-Naproxen (Standard)	COX Autophagy	Inflammation/Immunology Cancer
Naproxen (Standard) is the analytical standard of Naproxen. This product is intended for research and analytical applications. Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-W339645

Naproxen ethyl ester (S)-Naproxen ethyl ester	Others	Inflammation/Immunology
Naproxen ethyl ester ((S)-Naproxen ethyl ester) is a nonsteroidal anti-inflammatory drug with activity in relieving pain, fever, swelling and stiffness. Naproxen ethyl ester exerts its effects by inhibiting non-selective cyclooxygenase (COX). The R-(-)-isomer of Naproxen ethyl ester shows stronger immunogenicity, and the Michaelis-Menten parameter of its catalytic reaction is K(M)=6.67 mM, and the catalytic efficiency is 5.8 x 10^4 times higher than that of the non-catalytic reaction .

HY-15030AR

Naproxen sodium (Standard)	Autophagy COX	Inflammation/Immunology Cancer
Naproxen (sodium) (Standard) is the analytical standard of Naproxen (sodium). This product is intended for research and analytical applications. Naproxen sodium is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-15030S1

Naproxen-d3 (S)-Naproxen-d₃	Isotope-Labeled Compounds	Others
Naproxen-d₃ is the deuterium labeled Naproxen. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-B2121R

6-Methoxy-2-naphthoic acid (Standard) Naproxen impurity O (Standard)	iGluR	Neurological Disease
6-Methoxy-2-naphthoic acid (Standard) is the analytical standard of 6-Methoxy-2-naphthoic acid. This product is intended for research and analytical applications. 6-Methoxy-2-naphthoic acid is an NMDA receptor modulator extracted from patent WO 2012019106 A2.

HY-15029R

*(±)-Naproxen* (Standard)**	COX	Inflammation/Immunology Cancer
(±)-Naproxen (Standard) is the analytical standard of (±)-Naproxen. This product is intended for research and analytical applications. (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.

HY-15029

(±)-Naproxen (Rac)-Naproxen; 2-(6-Methoxynaphthalen-2-yl)propanoic acid	COX	Inflammation/Immunology Cancer
(±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively.

HY-132405S

*Desmethyl Naproxen-d3*	COX Autophagy	Others
Desmethyl Naproxen-d₃ is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen is the metabolite of anti-inflammatory agent Naproxen[1].

HY-15029S

*(±)-Naproxen-d3* (Rac)-Naproxen-d₃	COX Isotope-Labeled Compounds	Inflammation/Immunology
(±)-Naproxen-d₃ is the deuterium labeled (±)-Naproxen. (±)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID)[1].

HY-15029S2

*(±)-Naproxen-13C,d3*	COX	Cancer
(±)-Naproxen- ¹³C,d₃ is the deuterium and ¹³C labeled (±)-Naproxen[1]. (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.

HY-15029S1

*(±)-Naproxen-d3-1* (Rac)-Naproxen-d₃-1 (α-methyl-d₃)	COX Isotope-Labeled Compounds	Others
(±)-Naproxen-d₃-1 is the deuterium labeled (±)-Naproxen[1].

HY-131495

(S)-6-O-Desmethylnaproxen (S)-6-Desmethyl Naproxen	Others	Inflammation/Immunology
(S)-6-O-Desmethylnaproxen ((S)-6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen). (S)-6-O-Desmethylnaproxen is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

HY-Y0038

2-Bromo-6-methoxynaphthalene	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-Y0038R

2-Bromo-6-methoxynaphthalene (Standard)	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene (Standard) is the analytical standard of 2-Bromo-6-methoxynaphthalene. This product is intended for research and analytical applications. 2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-131495R

(S)-6-O-Desmethylnaproxen (Standard)	Others	Inflammation/Immunology
(S)-6-O-Desmethylnaproxen (Standard) is the analytical standard of (S)-6-O-Desmethylnaproxen. This product is intended for research and analytical applications. (S)-6-O-Desmethylnaproxen ((S)-6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen). (S)-6-O-Desmethylnaproxen is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

HY-14931

Naproxcinod AZD 3582; HCT 3012; NitroNaproxen	COX	Inflammation/Immunology
Naproxcinod (Nitronaproxen) is the first in class of cyclooxygenase (COX)-inhibiting nitric oxide donators (CINODs). Naproxcinod shows analgesic and anti-inflammatory effects, it can be used for the research of osteoarthritis and inflammation .

HY-118756

Anirolac RS37326	Others	Inflammation/Immunology
Anirolac (RS37326) is a nonsteroidal anti-inflammatory agent with analgesic activity. Anirolac showed analgesic efficacy comparable to that of naproxen in suppressing moderate or severe postpartum uterine pain. Anirolac induced significantly higher analgesia scores than placebo within 6 hours, especially at the 100 mg dose. Anirolac effectively relieved pain and showed a stronger analgesic effect than placebo in every assessment .

Cat. No.	Product Name

HY-L130

Non-steroidal Anti-Inflammatory Compound Library	614 compounds
Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic and antipyretic activity, and are among the most widely used drugs worldwide. The most prominent NSAIDs are aspirin, ibuprofen, and naproxen. The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX), based on which NSAIDs can be classified into two types: non-selective and COX-2 selective. Most NSAIDs are non-selective and inhibit both COX-1 and COX-2 activity. MCE offers a unique collection of 614 non-steroidal compounds with identified anti-inflammatory activity. MCE non-steroidal anti-inflammatory library is a useful tool for the study of anti-inflammatory drugs and pharmacology.

Non-steroidal Anti-Inflammatory Compound Library

614 compounds

Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic and antipyretic activity, and are among the most widely used drugs worldwide. The most prominent NSAIDs are aspirin, ibuprofen, and naproxen.

The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX), based on which NSAIDs can be classified into two types: non-selective and COX-2 selective. Most NSAIDs are non-selective and inhibit both COX-1 and COX-2 activity.

MCE offers a unique collection of 614 non-steroidal compounds with identified anti-inflammatory activity. MCE non-steroidal anti-inflammatory library is a useful tool for the study of anti-inflammatory drugs and pharmacology.

Cat. No.	Product Name	Type

HY-W699926

*(R)-Naproxen* acyl-β-D-glucuronide** (R)-Naproxen-β-D-glucuronide	Cell Assay Reagents
(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a compound metabolite with anti-inflammatory activity. (R)-Naproxen acyl-β-D-glucuronide can serve as a sensitive fluorescent substrate for proglutamyl peptidase 1, which produces a blue reaction after cleavage.

Cat. No.	Product Name	Chemical Structure