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Results for "

Nevirapine

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10570
    Nevirapine
    4 Publications Verification

    BI-RG 587; NSC 641530; NVP

    		 HIV Reverse Transcriptase Parasite Infection Cancer
    Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
    Nevirapine
  • HY-10570S
    Nevirapine-d4

    		Isotope-Labeled Compounds HIV Reverse Transcriptase Neurological Disease
    Nevirapine-d4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].
    Nevirapine-d4
  • HY-10570S1
    Nevirapine-d3

    		Isotope-Labeled Compounds HIV Reverse Transcriptase Infection Cancer
    Nevirapine-d3 (BI-RG 587-d3) is the deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].
    Nevirapine-d3
  • HY-167746
    Nevirapine quinone methide

    		Others Infection
    Nevirapine quinone methide is an active metabolite of Nevirapine, serving as a non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infection and AIDS. Nevirapine quinone methide is associated with severe skin and liver injuries due to its metabolic activation pathways. Nevirapine quinone methide has been shown to inhibit CYP3A4, which could contribute to its hepatic toxicity.
    Nevirapine quinone methide
  • HY-10570R
    Nevirapine (Standard)

    BI-RG 587 (Standard); NSC 641530 (Standard); NVP (Standard)

    		 HIV Reverse Transcriptase Parasite Infection Cancer
    Nevirapine (Standard) is the analytical standard of Nevirapine. This product is intended for research and analytical applications. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
    Nevirapine (Standard)
  • HY-148642
    12-Hydroxynevirapine

    12-hydroxy-NVP; 12-OH-NVP

    		 Drug Metabolite Infection
    12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine .
    12-Hydroxynevirapine
  • HY-123330
    GW695634

    		HIV Reverse Transcriptase Infection
    GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses .
    GW695634

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