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Nogo

" in MedChemExpress (MCE) Product Catalog:

By Research Areas:	Inflammation/Immunology (3) Neurological Disease (1)

2

Peptides

2

Inhibitory Antibodies

4

Recombinant Proteins

3

Antibodies

Cat. No.	Product Name	Target	Research Area

NEP(1-40) 1 Publications Verification	Peptides	Inflammation/Immunology
NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition .

NEP(1-40) TFA	Peptides	Inflammation/Immunology
NEP(1-40) TFA is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition .

Cat. No.	Product Name	Target	Research Area

*Anti-Nogo* Receptor/NgR Antibody**	Inhibitory Antibodies	Inflammation/Immunology

Ozanezumab GSK1223249	Inhibitory Antibodies	Neurological Disease
Ozanezumab (GSK1223249) is an *anti-Nogo-A* (neurite outgrowth inhibitor A) monoclonal antibody. Ozanezumab can be used in amyotrophic lateral sclerosis (ALS) and multiple sclerosis research .

Species:	Human (2) Mouse (1) Cynomolgus (1)
Tag:	His (4)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source

	Nogo Receptor/NgR Protein, Human (HEK293, His) Reticulon-4 Receptor; Nogo Receptor; NgR; Nogo-66 Receptor; RTN4R; NogoR	Human	HEK293
	Nogo receptor/NgR protein is a multifunctional receptor for RTN4, OMG and MAG, mediating a variety of cellular responses. It also interacts with the sialylated gangliosides GT1b and GM1, chondroitin sulfate proteoglycans, and heparin. Nogo Receptor/NgR Protein, Human (HEK293, His) is the recombinant human-derived Nogo Receptor/NgR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Nogo Receptor/NgR Protein, Human (HEK293, His) is 421 a.a., with molecular weight of 60-90 kDa.

	Nogo Receptor/NgR Protein, Mouse (HEK293, His) Reticulon-4 Receptor; Nogo Receptor; NgR; Nogo-66 Receptor; RTN4R; NogoR	Mouse	HEK293
	Nogo receptor/NgR proteins act as receptors for RTN4, OMG, MAG, and sialylated gangliosides. It also binds chondroitin sulfate proteoglycans and heparin. Nogo Receptor/NgR Protein, Mouse (HEK293, His) is the recombinant mouse-derived Nogo Receptor/NgR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Nogo Receptor/NgR Protein, Mouse (HEK293, His) is 421 a.a., with molecular weight of 75-85 kDa.

	RTN4RL1/NgR3 Protein, Human (HEK293, His) Reticulon-4 Receptor-Like 1; Nogo Receptor-Like 2; Nogo-66 Receptor Homolog 2; Nogo-66 Receptor-Related Protein 3; NgR3; RTN4RL1; NGRH2; NGRL2	Human	HEK293
	The RTN4RL1/NgR3 protein is a cell surface receptor that functionally affects postnatal brain development and axonal regeneration in the adult central nervous system. It aids in axonal migration across the midline of the brain and formation of the corpus callosum. RTN4RL1/NgR3 Protein, Human (HEK293, His) is the recombinant human-derived RTN4RL1/NgR3 protein, expressed by HEK293 , with C-6*His labeled tag.

	Nogo Receptor/NgR Protein, Cynomolgus (HEK293, His) Nogo receptor; RTN4R; NogoR; NgR1; Nogo-66 receptor; NGR	Cynomolgus	HEK293
	Nogo Receptor/NgR Protein functions as a versatile receptor for RTN4, OMG, and MAG, broadening its recognition to include sialylated gangliosides GT1b and GM1, chondroitin sulfate proteoglycans, and heparin. NGFR coreceptor activation initiates Rho-mediated actin cytoskeleton reorganization, leading to axonal growth inhibition. NgR plays a crucial role in axon regeneration and neuronal plasticity in the adult central nervous system, contributing to postnatal brain development, axon migration, and corpus callosum formation. It also protects motoneurons against apoptosis, potentially mediated by its interaction with MAG. Collaborating with RTN4 and LINGO1, NgR regulates neuronal precursor cell motility during cortical development. As a homodimer, it engages in a complex molecular network with OMG, MAG, RTN4, NGFR, LINGO1, KIAA0319L, and OLFM1, revealing its multifaceted roles in cellular processes and neural development. Nogo Receptor/NgR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Nogo Receptor/NgR protein, expressed by HEK293, with C-His labeled tag. The total length of Nogo Receptor/NgR Protein, Cynomolgus (HEK293, His) is 421 a.a., with molecular weight of 60-73 kDa.

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Cat. No.	Compare	Product Name	Application	Reactivity

	Nogo Receptor Antibody (YA2405) NgR; Nogo 66 receptor; Nogo receptor; Nogor; Reticulon 4 receptor; Rtn4r	WB, IP	Human, Mouse
	Nogo Receptor Antibody (YA2405) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2405), targeting Nogo Receptor, with a predicted molecular weight of 51 kDa (observed band size: 66 kDa). Nogo Receptor Antibody (YA2405) can be used for WB, IP experiment in human, mouse background.

	Nogo Antibody (YA1420) ASY; Foocen; NI220/250; Nogo; NogoC; NSP; rat N; RTN X; Rtn4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; Vp20	WB, IHC-P, ICC/IF, IP, FC	Human
	Nogo Antibody (YA1420) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1420), targeting Nogo, with a predicted molecular weight of 130 kDa (observed band size: 40-55 kDa). Nogo Antibody (YA1420) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.

	Nogo B Receptor Antibody (YA1414) NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199	WB	Human, Mouse, Rat
	Nogo B Receptor Antibody (YA1414) is a biotin-conjugated non-conjugated IgG antibody, targeting Nogo B Receptor, with a predicted molecular weight of 33 kDa (observed band size: 33 kDa). Nogo B Receptor Antibody (YA1414) can be used for WB experiment in human, mouse, rat background.

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