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ODC

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By Targets:	Endogenous Metabolite (2) Parasite (2) PKC (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (9) Neurological Disease (2)
Oligonucleotides:	Pre-designed siRNA Sets (1) Solubilizing Agents (1) Freeze-drying Protective Agents (1) siRNAs (1)

10

Inhibitors & Agonists

3

Natural
Products

2

Recombinant Proteins

1

Antibodies

2

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Protein kinase inhibitor H-7 dihydrochloride	PKC	Cancer
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced *ODC* (ornithine decarboxylase) .

Herbacetin 4 Publications Verification	Others	Cancer
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

L-Eflornithine monohydrochloride L-DFMO monohydrochloride; ; L-RMI71782 monohydrochloride; L-α-difluoromethylornithine monohydrochloride	Parasite	Cancer
L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

L-Asparagine 2 Publications Verification (-)-Asparagine; Asn; Asparamide	Endogenous Metabolite	Neurological Disease Cancer
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity .

ODC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ODC1 Human Pre-designed siRNA Set A contains three designed siRNAs for ODC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ODC1 Human Pre-designed siRNA Set A ODC1 Human Pre-designed siRNA Set A

L-Asparagine (Standard)	Endogenous Metabolite	Neurological Disease Cancer
L-Asparagine (Standard) is the analytical standard of L-Asparagine. This product is intended for research and analytical applications. L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity . In Vitro:L-Asparagine (0.03 mM) can reverse the proliferation decline of six human cancer cells induced by ASNS siRNA knockdown . L-Asparagine (10 mM, 4 h) can stimulate ODC activity and proliferation in IPEC-J2 cells .

Herbacetin (Standard)	Others	Cancer
Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

NCAO	Others	Cancer
N-ω-chloroacetyl-L-ornithine (NCAO) is a potent reversible competitive ornithine decarboxylase (ODC) inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC₅₀ values ranging from 1 to 50.6 µM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma (Ag8) cell line. NCAO is promising for research of antitumor agents .

L-Eflornithine L-DFMO; L-RMI71782; L-α-difluoromethylornithine	Parasite	Cancer
L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

Methyl-4-oxoretinoate	Others	Cancer
Methyl-4-oxoretinoate is a derivative of Retinoic acid (HY-14649). Methyl-4-oxoretinoate inhibits TPA (HY-18739)-induced ornithine decarboxylase (ODC) activity, and carcinogen-induced papillomas in mouse skin .

Species:	Human (2)
Tag:	SUMO (1) His (2) T7 (1) Myc (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	ODC1 Protein, Human (HEK293, His-T7) Ornithine decarboxylase; ODC1;	Human	E. coli
	The ODC1 protein is an important enzyme that catalyzes the epimerization of NAD(P)HX, a damaged NAD(P)H derivative. This activity is critical for subsequent repair by S-specific NAD(P)H hydrate dehydratase. ODC1 Protein, Human (HEK293, His-T7) is the recombinant human-derived ODC1 protein, expressed by E. coli , with N-T7, C-6*His labeled tag.

	ODC1 Protein, Human (His-SUMO, Myc) Ornithine decarboxylase; ODC1;	Human	E. coli
	The ODC1 protein is an important enzyme that catalyzes the epimerization of NAD(P)HX, a damaged NAD(P)H derivative. This activity is critical for subsequent repair by S-specific NAD(P)H hydrate dehydratase. ODC1 Protein, Human (His-SUMO, Myc) is the recombinant human-derived ODC1, expressed by E. coli , with N-10*His, C-Myc, N-SUMO labeled tag. ,

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	ODC1 Antibody (YA2123) DODC1; ODC; ODC1; ODC2; RNODC	WB	Human, Mouse, Rat
	ODC1 Antibody (YA2123) is a biotin-conjugated non-conjugated IgG antibody, targeting ODC1, with a predicted molecular weight of 51 kDa (observed band size: 51 kDa). ODC1 Antibody (YA2123) can be used for WB experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

L-Asparagine 2 Publications Verification (-)-Asparagine; Asn; Asparamide		Freeze-drying Protective Agents Solubilizing Agents
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity .

ODC1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
ODC1 Human Pre-designed siRNA Set A contains three designed siRNAs for ODC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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