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Oligomeric acid

" in MedChemExpress (MCE) Product Catalog:

15

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1

Biochemical Assay Reagents

1

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1

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4

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3

Recombinant Proteins

1

Isotope-Labeled Compounds

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Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-127074
    Chlorendic acid

    HET acid

    		 Biochemical Assay Reagents Others
    Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .
    Chlorendic acid
  • HY-Y1883
    Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant

    		Biochemical Assay Reagents Others
    Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is an oligomeric blend that can be used for biochemical research .
    Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant
  • HY-138887
    Decyl maltose neopentyl glycol

    DMNG

    		 Biochemical Assay Reagents Others
    Decyl maltose neopentyl glycol (DMNG) is the neopentyl glycol detergent that does not disrupt the AlkB oligomeric state. AlkB is a nonheme di-iron alkane hydroxylase .
    Decyl maltose neopentyl glycol
  • HY-P99835
    Crenezumab

    MABT 5102A; RG 7412

    		 Amyloid-β Neurological Disease
    Crenezumab (MABT 5102A; RG 7412) is a fully humanized anti-Aβ monoclonal antibody that binds multiple forms of Aβ, such as soluble, oligomeric and fibrillar, for use in Alzheimer's disease research .
    Crenezumab
  • HY-N7046
    Silybin B

    Silibinin B

    		 Amyloid-β Neurological Disease Cancer
    Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B
  • HY-126419
    Kobophenol A

    		SARS-CoV PKC Infection
    Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 µM .
    Kobophenol A
  • HY-115533
    LBL1

    		DNA/RNA Synthesis Others
    LBL1 is a ligand for lamins (especially lamin A, LA) in the nucleus, that stabilizes the oligomeric state of LA, and affects the assembly state of LA. LBL1 can be used to study the assembly state and dynamic changes of LA .
    LBL1
  • HY-149582
    Aβ-IN-7

    		Amyloid-β Neurological Disease
    Aβ-IN-7 (compound 5a) is a potent inhibitor of the Aβ aggregation. Aβ-IN-7 with 50 μM stabilize Aβ monomers in the small oligomeric species and prolong the nucleation process. Aβ-IN-7 inhibits Aβ fibril formation better than Aβ-IN-8 (HY-149583) in 50 μM .
    Aβ-IN-7
  • HY-N7046R
    Silybin B (Standard)

    		Amyloid-β Neurological Disease Cancer
    Silybin B (Standard) is the analytical standard of Silybin B. This product is intended for research and analytical applications. Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B (Standard)
  • HY-N7046S
    Silybin B-d3

    Silibinin B-d3

    		 Isotope-Labeled Compounds Amyloid-β Neurological Disease Cancer
    Silybin B-d3 (Silibinin B-d3) is deuterium labeled Silybin B. Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B-d3
  • HY-101855
    Emrusolmin

    Anle138b

    		 Amyloid-β Neurological Disease
    Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology .
    Emrusolmin
  • HY-149246
    Aβ-IN-6

    		Amyloid-β Keap1-Nrf2 Neurological Disease Inflammation/Immunology
    Aβ-IN-6 reduces pro-inflammatory cytokine release from microglia cells. Aβ-IN-6 significantly induces Nrf2 nuclear translocation and hamperes Aβ oligomers formation. Aβ-IN-6 exerts a consistent neuroprotective effect by modulating the redox-sensitive signalling pathways in vivo oxidative stress model. Aβ-IN-6 is an orally active and has antiinflammatory, Antioxidant and Anti-oligomeric activity. Aβ-IN-6 has the potential for Alzheimer's disease (AD) research .
    Aβ-IN-6
  • HY-113402A
    Gamma-glutamylcysteine TFA
    2 Publications Verification

    γ-Glutamylcysteine TFA

    		 Interleukin Related TNF Receptor Endogenous Metabolite Inflammation/Immunology
    Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes .
    Gamma-glutamylcysteine TFA
  • HY-100958
    4-DAMP
    3 Publications Verification

    4-DAMP methiodide

    		 mAChR Apoptosis MMP EGFR Interleukin Related Inflammation/Immunology Cancer
    4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
    4-DAMP
  • HY-151746
    N3-Gly-Gly-Gly-OH

    		ADC Linker Others
    N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved . N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-Gly-Gly-Gly-OH

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