Decyl maltose neopentyl glycol (Synonyms: DMNG)

Name: Decyl maltose neopentyl glycol
Brand: MedChemExpress
SKU: HY-138887
Rating: 4.5 (1 reviews)

Cat. No.: HY-138887 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Decyl maltose neopentyl glycol (DMNG) is the neopentyl glycol detergent that does not disrupt the AlkB oligomeric state. AlkB is a nonheme di-iron alkane hydroxylase.

For research use only. We do not sell to patients.

Decyl maltose neopentyl glycol Chemical Structure

CAS No. : 1257852-99-5

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 209	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 209	In-stock	Estimated Time of Arrival: December 31
Solid
25 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Description

Decyl maltose neopentyl glycol (DMNG) is the neopentyl glycol detergent that does not disrupt the AlkB oligomeric state. AlkB is a nonheme di-iron alkane hydroxylase^[1].

In Vitro

Decyl maltose neopentyl glycol (DMNG) preserves the P. putida AlkB (PpAlkB-SII) hydroxylase activity after purification^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

949.08

Formula

C₄₃H₈₀O₂₂

CAS No.

1257852-99-5

Appearance

Solid

Color

White to off-white

SMILES

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)O[C@H]1OCC(CCCCCCCC)(CCCCCCCC)CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (105.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0537 mL	5.2683 mL	10.5365 mL
5 mM	0.2107 mL	1.0537 mL	2.1073 mL
10 mM	0.1054 mL	0.5268 mL	1.0537 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (2.63 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (2.63 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (2.63 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (257 KB) HNMR (308 KB) MS (199 KB)

Handling Instructions (2659 KB)

References

[1]. Hernan Alonso, et al. Characterization and two-dimensional crystallization of membrane component AlkB of the medium-chain alkane hydroxylase system from Pseudomonas putida GPo1. Appl Environ Microbiol. 2012 Nov;78(22):7946-53. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0537 mL	5.2683 mL	10.5365 mL	26.3413 mL
	5 mM	0.2107 mL	1.0537 mL	2.1073 mL	5.2683 mL
	10 mM	0.1054 mL	0.5268 mL	1.0537 mL	2.6341 mL
	15 mM	0.0702 mL	0.3512 mL	0.7024 mL	1.7561 mL
	20 mM	0.0527 mL	0.2634 mL	0.5268 mL	1.3171 mL
	25 mM	0.0421 mL	0.2107 mL	0.4215 mL	1.0537 mL
	30 mM	0.0351 mL	0.1756 mL	0.3512 mL	0.8780 mL
	40 mM	0.0263 mL	0.1317 mL	0.2634 mL	0.6585 mL
	50 mM	0.0211 mL	0.1054 mL	0.2107 mL	0.5268 mL
	60 mM	0.0176 mL	0.0878 mL	0.1756 mL	0.4390 mL
	80 mM	0.0132 mL	0.0659 mL	0.1317 mL	0.3293 mL
	100 mM	0.0105 mL	0.0527 mL	0.1054 mL	0.2634 mL

Decyl maltose neopentyl glycol Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Decyl maltose neopentyl glycol (Synonyms: DMNG)

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Complete Stock Solution Preparation Table

Decyl maltose neopentyl glycol Related Classifications

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